An Automated, Home-Cage, Video Monitoring-based Mouse Frailty Index Detects Age-associated Morbidity in C57BL/6 and Diversity Outbred Mice

Abstract Frailty indexes (FIs) provide quantitative measurements of nonspecific health decline and are particularly useful as longitudinal monitors of morbidity in aging studies. For mouse studies, frailty assessments can be taken noninvasively, but they require handling and direct observation that...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2023-05, Vol.78 (5), p.762-770
Hauptverfasser:	Ruby, J Graham, Di Francesco, Andrea, Ylagan, Paulo, Luo, Angela, Keyser, Robert, Williams, Owen, Spock, Sarah, Li, Wenzhou, Vongtharangsy, Nalien, Chatterjee, Sandip, Sloan, Cricket A, Ledogar, Charles, Kuiper, Veronica, Kite, Janessa, Cosino, Marcelo, Cha, Paulyn, Karlsson, Eleanor M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging Animals Collaborative Cross Mice Frail Elderly Frailty Frailty - diagnosis Genetics Geriatric Assessment Gerontology Humans Indexes Mice Mice, Inbred C57BL Morbidity THE JOURNAL OF GERONTOLOGY: Biological Sciences Workplace diversity
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