[18F]FDG Uptake and Expression of Immunohistochemical Markers Related to Glycolysis, Hypoxia, and Proliferation in Indeterminate Thyroid Nodules

Purpose The current study explored the association between 2-[ 18 F]fluoro-2-deoxy-D-glucose ([ 18 F]FDG) uptake and the quantitative expression of immunohistochemical markers related to glucose metabolism, hypoxia, and cell proliferation in benign and malignant thyroid nodules of indeterminate cyto...

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Veröffentlicht in:	Molecular imaging and biology 2023-06, Vol.25 (3), p.483-494
Hauptverfasser:	de Koster, Elizabeth J., van Engen-van Grunsven, Adriana C. H., Bussink, Johan, Frielink, Cathelijne, de Geus-Oei, Lioe-Fee, Kusters, Benno, Peters, Hans, Oyen, Wim J. G., Vriens, Dennis
Format:	Artikel
Sprache:	eng
Schlagworte:	Benign Cancer Carbonic anhydrase Carbonic anhydrases Cell proliferation Cluster analysis Correlation coefficient Correlation coefficients Cytology Fluorine isotopes Fluorodeoxyglucose F18 - metabolism Glucose Glucose metabolism Glucose Transporter Type 1 - metabolism Glycolysis Growth factors Hexokinase Humans Hypoxia Hypoxia-inducible factor 1 Hypoxia-inducible factor 1a Hypoxia-inducible factors Imaging Iodides Medicine Medicine & Public Health Nodules Positron emission tomography Positron Emission Tomography Computed Tomography Positron-Emission Tomography - methods Radiology Radiopharmaceuticals Research Article Thyroid Thyroid cancer Thyroid carcinoma Thyroid gland Thyroid Neoplasms Thyroid Nodule - diagnostic imaging Thyroid Nodule - surgery Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism
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