Efficacy of glucocorticoids, chloroquine and vitamin A on cytokine release syndrome: a network pharmacology study

To verify the efficacy of glucocorticoids, chloroquine and vitamin A in the treatment of cytokine release syndrome (CRS), and to investigate the underlying mechanisms, based on network pharmacology. We used network pharmacology analysis and found 20 co-targeted genes of glucocorticoids, chloroquine,...

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Veröffentlicht in:	Journal of traditional Chinese medicine 2022-02, Vol.42 (1), p.116-121
Hauptverfasser:	Zhang, Jing, Zhu, Jing-Jing, He, Si-Qi, Wang, Jian-Xun
Format:	Artikel
Sprache:	eng
Schlagworte:	Chloroquine - pharmacology Cytokine Release Syndrome Drugs, Chinese Herbal - pharmacology Glucocorticoids Humans Interleukin-10 Interleukin-2 Interleukin-4 Luteolin Molecular Docking Simulation Network Pharmacology Tumor Necrosis Factor-alpha - metabolism Vitamin A
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