HEMATOLOGICAL INDICES RELATED TO VITAMIN D DEFICIENCY IN OBESE CHILDREN
Vitamin D is involved in differentiation and induction of erythropoiesis in bone marrow cells. We compared the serum 25(OH) vitamin D level in obese children control and found correlations between vitamin D level and hematological indices in obese children. 25 overweight and obese patients and 15 no...
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Veröffentlicht in: | Acta endocrinologica (Bucharest, Romania : 2005) Romania : 2005), 2022-10, Vol.18 (4), p.488-493 |
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creator | Virgolici, B Mohora, M Virgolici, H M Posea, M Martin, R E |
description | Vitamin D is involved in differentiation and induction of erythropoiesis in bone marrow cells.
We compared the serum 25(OH) vitamin D level in obese children
control and found correlations between vitamin D level and hematological indices in obese children.
25 overweight and obese patients and 15 normal weight children were enrolled in an observational study .
In obese children, the serum level of 25(OH) vitamin D was significantly (p |
doi_str_mv | 10.4183/aeb.2022.488 |
format | Article |
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We compared the serum 25(OH) vitamin D level in obese children
control and found correlations between vitamin D level and hematological indices in obese children.
25 overweight and obese patients and 15 normal weight children were enrolled in an observational study .
In obese children, the serum level of 25(OH) vitamin D was significantly (p<0.04) lower (20.60 ng/mL) compared with the value from normal weight ones (25.63 ng/mL) and the body fat percentage BFP was higher. We found a positive correlation (r=0.44, p<0.05) between serum vitamin D and hemoglobin level and a negative one between serum vitamin D and the number of platelets (r= -0.43, p<0.05). Also, the serum iron was at the lower normal limit in the obese children and negatively correlated with the percent of the body fat (r= -0,62, p<0.05).
Obese children have vitamin D deficiency. The hemoglobin level and the number of platelets are correlated with the serum level of 25(OH) vitamin D. Supplements with vitamin D may have pleiotropic effects, including those on bone marrow activity.</description><identifier>ISSN: 1841-0987</identifier><identifier>EISSN: 1843-066X</identifier><identifier>DOI: 10.4183/aeb.2022.488</identifier><identifier>PMID: 37152869</identifier><language>eng</language><publisher>Romania: Carol Davila University Press</publisher><ispartof>Acta endocrinologica (Bucharest, Romania : 2005), 2022-10, Vol.18 (4), p.488-493</ispartof><rights>2022 Acta Endocrinologica (Buc).</rights><rights>2022 Acta Endocrinologica (Buc) 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162821/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162821/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37152869$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Virgolici, B</creatorcontrib><creatorcontrib>Mohora, M</creatorcontrib><creatorcontrib>Virgolici, H M</creatorcontrib><creatorcontrib>Posea, M</creatorcontrib><creatorcontrib>Martin, R E</creatorcontrib><title>HEMATOLOGICAL INDICES RELATED TO VITAMIN D DEFICIENCY IN OBESE CHILDREN</title><title>Acta endocrinologica (Bucharest, Romania : 2005)</title><addtitle>Acta Endocrinol (Buchar)</addtitle><description>Vitamin D is involved in differentiation and induction of erythropoiesis in bone marrow cells.
We compared the serum 25(OH) vitamin D level in obese children
control and found correlations between vitamin D level and hematological indices in obese children.
25 overweight and obese patients and 15 normal weight children were enrolled in an observational study .
In obese children, the serum level of 25(OH) vitamin D was significantly (p<0.04) lower (20.60 ng/mL) compared with the value from normal weight ones (25.63 ng/mL) and the body fat percentage BFP was higher. We found a positive correlation (r=0.44, p<0.05) between serum vitamin D and hemoglobin level and a negative one between serum vitamin D and the number of platelets (r= -0.43, p<0.05). Also, the serum iron was at the lower normal limit in the obese children and negatively correlated with the percent of the body fat (r= -0,62, p<0.05).
Obese children have vitamin D deficiency. The hemoglobin level and the number of platelets are correlated with the serum level of 25(OH) vitamin D. Supplements with vitamin D may have pleiotropic effects, including those on bone marrow activity.</description><issn>1841-0987</issn><issn>1843-066X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNpVkEFPwjAUgBujEURvns2OHhz2vY6uO5m5FViCkMA0emq6rVPMYLiBif_eIUj01Jf0y_dePkIugXYdEOxWm6SLFLHrCHFE2iAcZlPOn49_ZrCpJ9wWOavrd0p7ggKckhZzoYeCe20yGMoHP56MJoMo8EdWNA6jQM6sqRz5sQyteGI9RbH_EI2t0AplPwoiOQ5eGs6a3MuZtIJhNAqncnxOTnJd1OZi_3bIY1_GwdDem-2UObi2ea5N7kDKEkR0ci9J8sz1tKsZ9TRqw5jGDGmeUe3xlKXgOQ5kwnBMEiPAYx1yt_OuNsnCZKlZritdqFU1X-jqS5V6rv7_LOdv6rX8VECBo0BoDNd7Q1V-bEy9Vot5nZqi0EtTbmqFAgCBuwwb9GaHplVZ15XJD3uAqm181cRX2_iqid_gV39vO8C_tdk3gll5-A</recordid><startdate>20221001</startdate><enddate>20221001</enddate><creator>Virgolici, B</creator><creator>Mohora, M</creator><creator>Virgolici, H M</creator><creator>Posea, M</creator><creator>Martin, R E</creator><general>Carol Davila University Press</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20221001</creationdate><title>HEMATOLOGICAL INDICES RELATED TO VITAMIN D DEFICIENCY IN OBESE CHILDREN</title><author>Virgolici, B ; Mohora, M ; Virgolici, H M ; Posea, M ; Martin, R E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c342t-6faef41c3b2224f9bbfd79a7a309a2ae33a2d20fd0a96c3c19441d8e62bbe8193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Virgolici, B</creatorcontrib><creatorcontrib>Mohora, M</creatorcontrib><creatorcontrib>Virgolici, H M</creatorcontrib><creatorcontrib>Posea, M</creatorcontrib><creatorcontrib>Martin, R E</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Acta endocrinologica (Bucharest, Romania : 2005)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Virgolici, B</au><au>Mohora, M</au><au>Virgolici, H M</au><au>Posea, M</au><au>Martin, R E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>HEMATOLOGICAL INDICES RELATED TO VITAMIN D DEFICIENCY IN OBESE CHILDREN</atitle><jtitle>Acta endocrinologica (Bucharest, Romania : 2005)</jtitle><addtitle>Acta Endocrinol (Buchar)</addtitle><date>2022-10-01</date><risdate>2022</risdate><volume>18</volume><issue>4</issue><spage>488</spage><epage>493</epage><pages>488-493</pages><issn>1841-0987</issn><eissn>1843-066X</eissn><abstract>Vitamin D is involved in differentiation and induction of erythropoiesis in bone marrow cells.
We compared the serum 25(OH) vitamin D level in obese children
control and found correlations between vitamin D level and hematological indices in obese children.
25 overweight and obese patients and 15 normal weight children were enrolled in an observational study .
In obese children, the serum level of 25(OH) vitamin D was significantly (p<0.04) lower (20.60 ng/mL) compared with the value from normal weight ones (25.63 ng/mL) and the body fat percentage BFP was higher. We found a positive correlation (r=0.44, p<0.05) between serum vitamin D and hemoglobin level and a negative one between serum vitamin D and the number of platelets (r= -0.43, p<0.05). Also, the serum iron was at the lower normal limit in the obese children and negatively correlated with the percent of the body fat (r= -0,62, p<0.05).
Obese children have vitamin D deficiency. The hemoglobin level and the number of platelets are correlated with the serum level of 25(OH) vitamin D. Supplements with vitamin D may have pleiotropic effects, including those on bone marrow activity.</abstract><cop>Romania</cop><pub>Carol Davila University Press</pub><pmid>37152869</pmid><doi>10.4183/aeb.2022.488</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
title | HEMATOLOGICAL INDICES RELATED TO VITAMIN D DEFICIENCY IN OBESE CHILDREN |
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