Convergence of scaffold-guided bone regeneration principles and microvascular tissue transfer surgery

A preclinical evaluation using a regenerative medicine methodology comprising an additively manufactured medical-grade ε-polycaprolactone β-tricalcium phosphate (mPCL-TCP) scaffold with a corticoperiosteal flap was undertaken in eight sheep with a tibial critical-size segmental bone defect (9.5 cm ,...

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Veröffentlicht in:	Science advances 2023-05, Vol.9 (18), p.eadd6071-eadd6071
Hauptverfasser:	Sparks, David S, Savi, Flavia M, Dlaska, Constantin E, Saifzadeh, Siamak, Brierly, Gary, Ren, Edward, Cipitria, Amaia, Reichert, Johannes C, Wille, Marie-Luise, Schuetz, Michael A, Ward, Nicola, Wagels, Michael, Hutmacher, Dietmar W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedicine and Life Sciences Bone and Bones Bone Regeneration Male Organismal Biology Pilot Projects SciAdv r-articles Sheep Tibia Tissue Scaffolds
Online-Zugang:	Volltext
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