Association between the epigenetic lifespan predictor GrimAge and history of suicide attempt in bipolar disorder

Bipolar disorder (BD) has been previously associated with premature mortality and aging, including acceleration of epigenetic aging. Suicide attempts (SA) are greatly elevated in BD and are associated with decreased lifespan, biological aging, and poorer clinical outcomes. We investigated the relati...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2023-05, Vol.48 (6), p.954-962
Hauptverfasser:	Lima, Camila N C, Kovács, Emese H C, Mirza, Salahudeen, Del Favero-Campbell, Alexandra, Diaz, Alexandre Paim, Quevedo, Joao, Argue, Benney M R, Richards, Jenny Gringer, Williams, Aislinn, Wemmie, John A, Magnotta, Vincent A, Fiedorowicz, Jess G, Soares, Jair C, Gaine, Marie E, Fries, Gabriel R
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - genetics Bipolar disorder Bipolar Disorder - complications DNA Methylation Epigenesis, Genetic Epigenetics Humans Leptin Life span Longevity Morbidity Mortality Plasminogen activator inhibitors Replication Suicide Suicide, Attempted Suicides & suicide attempts
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