Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy

A study on dosimetric characteristics of silicon elastomer-based bolus was carried out using a Linear accelerator (Varian - Unique Performance). The study is performed to know if the silicone elastomer based bolus can be used in the radiotherapy. A bolus is a tissue equivalent material used to provi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Asian Pacific Journal of Cancer Prevention 2023-01, Vol.24 (1), p.141-147
Hauptverfasser: Boopathi, M, Khanna, D, Venkatraman, P, Varshini, R, Sureka, C S, Pooja, S
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 147
container_issue 1
container_start_page 141
container_title Asian Pacific Journal of Cancer Prevention
container_volume 24
creator Boopathi, M
Khanna, D
Venkatraman, P
Varshini, R
Sureka, C S
Pooja, S
description A study on dosimetric characteristics of silicon elastomer-based bolus was carried out using a Linear accelerator (Varian - Unique Performance). The study is performed to know if the silicone elastomer based bolus can be used in the radiotherapy. A bolus is a tissue equivalent material used to provide uniform dose to the uneven surface contours. It is exposed during the radiation therapy and also provides maximum dose (dmax) to treat surface tumors in case of high energy photons like megavoltage therapy photons. It is used in the case of external beam radiation therapy. In this study, the bolus was fabricated using PDMS substrate with a curing agent by the ratio of 10:1. The bolus was fabricated in two thicknesses 0.5cm and 1cm. The dosimetric characteristics like transmission factor, mass attenuation coefficient, durability, homogeneity, density test of the fabricated bolus were studied. The dosimetric characteristics of the silicone elastomer based bolus were studied over a period of one month by exposing it in a 6MV photon. The result of the study shows that the silicone elastomer based bolus fabricated, satisfies the dosimetric characteristics needed for a tissue equivalent bolus to be used in the radiation therapy. The fabricated bolus could increase the percentage surface dose, reduce skin-sparing effect, and protect OAR. The aim of this is to provide an adjustable, transparent, and easily fabricated, less expensive, nontoxic bolus which can be used in the radiotherapy.
doi_str_mv 10.31557/APJCP.2023.24.1.141
format Article
fullrecord <record><control><sourceid>pubmed_cross</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10152843</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>36708562</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3241-973d295d617a6ed81c3a96c5c6d9b0350b124c9f6f8e17a17835e7af55b492663</originalsourceid><addsrcrecordid>eNpVkNtKxDAQhoMont9AJC_QmnPaK3HX9cSCiwfwLkzT1I20zZJU0be3HtGrGWbm-wc-hA4oyTmVUh-dLK6mi5wRxnMmcppTQdfQNhNaZVqxh_U__RbaSemJECELLTfRFleaFFKxbdSeQRW9hcGHHkNf49OQfOeGcYanS4hgBxd9GrxNODT41rfejpezFtIQOhezCSRX40lonxO-T75_xLPXEemhxRMHHb6B2odh6SKs3vbQRgNtcvvfdRfdn83uphfZ_Pr8cnoyzyxngmal5jUrZa2oBuXqgloOpbLSqrqsCJekokzYslFN4cYTqgsunYZGykqUTCm-i46_clfPVedq6_ohQmtW0XcQ30wAb_5ver80j-HFUEIlKwQfE8RXgo0hpeiaX5gS86nffOo3H_oNE4aaUf-IHf59_Av9-ObvT0-Dog</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free E- Journals</source><creator>Boopathi, M ; Khanna, D ; Venkatraman, P ; Varshini, R ; Sureka, C S ; Pooja, S</creator><creatorcontrib>Boopathi, M ; Khanna, D ; Venkatraman, P ; Varshini, R ; Sureka, C S ; Pooja, S</creatorcontrib><description>A study on dosimetric characteristics of silicon elastomer-based bolus was carried out using a Linear accelerator (Varian - Unique Performance). The study is performed to know if the silicone elastomer based bolus can be used in the radiotherapy. A bolus is a tissue equivalent material used to provide uniform dose to the uneven surface contours. It is exposed during the radiation therapy and also provides maximum dose (dmax) to treat surface tumors in case of high energy photons like megavoltage therapy photons. It is used in the case of external beam radiation therapy. In this study, the bolus was fabricated using PDMS substrate with a curing agent by the ratio of 10:1. The bolus was fabricated in two thicknesses 0.5cm and 1cm. The dosimetric characteristics like transmission factor, mass attenuation coefficient, durability, homogeneity, density test of the fabricated bolus were studied. The dosimetric characteristics of the silicone elastomer based bolus were studied over a period of one month by exposing it in a 6MV photon. The result of the study shows that the silicone elastomer based bolus fabricated, satisfies the dosimetric characteristics needed for a tissue equivalent bolus to be used in the radiation therapy. The fabricated bolus could increase the percentage surface dose, reduce skin-sparing effect, and protect OAR. The aim of this is to provide an adjustable, transparent, and easily fabricated, less expensive, nontoxic bolus which can be used in the radiotherapy.</description><identifier>ISSN: 2476-762X</identifier><identifier>ISSN: 1513-7368</identifier><identifier>EISSN: 2476-762X</identifier><identifier>DOI: 10.31557/APJCP.2023.24.1.141</identifier><identifier>PMID: 36708562</identifier><language>eng</language><publisher>Thailand: West Asia Organization for Cancer Prevention</publisher><subject>Elastomers ; Humans ; Neoplasms - radiotherapy ; Phantoms, Imaging ; Photons - therapeutic use ; Radiometry ; Radiotherapy ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted ; Silicone Elastomers</subject><ispartof>Asian Pacific Journal of Cancer Prevention, 2023-01, Vol.24 (1), p.141-147</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3241-973d295d617a6ed81c3a96c5c6d9b0350b124c9f6f8e17a17835e7af55b492663</citedby><orcidid>000000152557212</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152843/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152843/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,861,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36708562$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Boopathi, M</creatorcontrib><creatorcontrib>Khanna, D</creatorcontrib><creatorcontrib>Venkatraman, P</creatorcontrib><creatorcontrib>Varshini, R</creatorcontrib><creatorcontrib>Sureka, C S</creatorcontrib><creatorcontrib>Pooja, S</creatorcontrib><title>Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy</title><title>Asian Pacific Journal of Cancer Prevention</title><addtitle>Asian Pac J Cancer Prev</addtitle><description>A study on dosimetric characteristics of silicon elastomer-based bolus was carried out using a Linear accelerator (Varian - Unique Performance). The study is performed to know if the silicone elastomer based bolus can be used in the radiotherapy. A bolus is a tissue equivalent material used to provide uniform dose to the uneven surface contours. It is exposed during the radiation therapy and also provides maximum dose (dmax) to treat surface tumors in case of high energy photons like megavoltage therapy photons. It is used in the case of external beam radiation therapy. In this study, the bolus was fabricated using PDMS substrate with a curing agent by the ratio of 10:1. The bolus was fabricated in two thicknesses 0.5cm and 1cm. The dosimetric characteristics like transmission factor, mass attenuation coefficient, durability, homogeneity, density test of the fabricated bolus were studied. The dosimetric characteristics of the silicone elastomer based bolus were studied over a period of one month by exposing it in a 6MV photon. The result of the study shows that the silicone elastomer based bolus fabricated, satisfies the dosimetric characteristics needed for a tissue equivalent bolus to be used in the radiation therapy. The fabricated bolus could increase the percentage surface dose, reduce skin-sparing effect, and protect OAR. The aim of this is to provide an adjustable, transparent, and easily fabricated, less expensive, nontoxic bolus which can be used in the radiotherapy.</description><subject>Elastomers</subject><subject>Humans</subject><subject>Neoplasms - radiotherapy</subject><subject>Phantoms, Imaging</subject><subject>Photons - therapeutic use</subject><subject>Radiometry</subject><subject>Radiotherapy</subject><subject>Radiotherapy Dosage</subject><subject>Radiotherapy Planning, Computer-Assisted</subject><subject>Silicone Elastomers</subject><issn>2476-762X</issn><issn>1513-7368</issn><issn>2476-762X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkNtKxDAQhoMont9AJC_QmnPaK3HX9cSCiwfwLkzT1I20zZJU0be3HtGrGWbm-wc-hA4oyTmVUh-dLK6mi5wRxnMmcppTQdfQNhNaZVqxh_U__RbaSemJECELLTfRFleaFFKxbdSeQRW9hcGHHkNf49OQfOeGcYanS4hgBxd9GrxNODT41rfejpezFtIQOhezCSRX40lonxO-T75_xLPXEemhxRMHHb6B2odh6SKs3vbQRgNtcvvfdRfdn83uphfZ_Pr8cnoyzyxngmal5jUrZa2oBuXqgloOpbLSqrqsCJekokzYslFN4cYTqgsunYZGykqUTCm-i46_clfPVedq6_ohQmtW0XcQ30wAb_5ver80j-HFUEIlKwQfE8RXgo0hpeiaX5gS86nffOo3H_oNE4aaUf-IHf59_Av9-ObvT0-Dog</recordid><startdate>20230101</startdate><enddate>20230101</enddate><creator>Boopathi, M</creator><creator>Khanna, D</creator><creator>Venkatraman, P</creator><creator>Varshini, R</creator><creator>Sureka, C S</creator><creator>Pooja, S</creator><general>West Asia Organization for Cancer Prevention</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/000000152557212</orcidid></search><sort><creationdate>20230101</creationdate><title>Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy</title><author>Boopathi, M ; Khanna, D ; Venkatraman, P ; Varshini, R ; Sureka, C S ; Pooja, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3241-973d295d617a6ed81c3a96c5c6d9b0350b124c9f6f8e17a17835e7af55b492663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Elastomers</topic><topic>Humans</topic><topic>Neoplasms - radiotherapy</topic><topic>Phantoms, Imaging</topic><topic>Photons - therapeutic use</topic><topic>Radiometry</topic><topic>Radiotherapy</topic><topic>Radiotherapy Dosage</topic><topic>Radiotherapy Planning, Computer-Assisted</topic><topic>Silicone Elastomers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boopathi, M</creatorcontrib><creatorcontrib>Khanna, D</creatorcontrib><creatorcontrib>Venkatraman, P</creatorcontrib><creatorcontrib>Varshini, R</creatorcontrib><creatorcontrib>Sureka, C S</creatorcontrib><creatorcontrib>Pooja, S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Asian Pacific Journal of Cancer Prevention</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boopathi, M</au><au>Khanna, D</au><au>Venkatraman, P</au><au>Varshini, R</au><au>Sureka, C S</au><au>Pooja, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy</atitle><jtitle>Asian Pacific Journal of Cancer Prevention</jtitle><addtitle>Asian Pac J Cancer Prev</addtitle><date>2023-01-01</date><risdate>2023</risdate><volume>24</volume><issue>1</issue><spage>141</spage><epage>147</epage><pages>141-147</pages><issn>2476-762X</issn><issn>1513-7368</issn><eissn>2476-762X</eissn><abstract>A study on dosimetric characteristics of silicon elastomer-based bolus was carried out using a Linear accelerator (Varian - Unique Performance). The study is performed to know if the silicone elastomer based bolus can be used in the radiotherapy. A bolus is a tissue equivalent material used to provide uniform dose to the uneven surface contours. It is exposed during the radiation therapy and also provides maximum dose (dmax) to treat surface tumors in case of high energy photons like megavoltage therapy photons. It is used in the case of external beam radiation therapy. In this study, the bolus was fabricated using PDMS substrate with a curing agent by the ratio of 10:1. The bolus was fabricated in two thicknesses 0.5cm and 1cm. The dosimetric characteristics like transmission factor, mass attenuation coefficient, durability, homogeneity, density test of the fabricated bolus were studied. The dosimetric characteristics of the silicone elastomer based bolus were studied over a period of one month by exposing it in a 6MV photon. The result of the study shows that the silicone elastomer based bolus fabricated, satisfies the dosimetric characteristics needed for a tissue equivalent bolus to be used in the radiation therapy. The fabricated bolus could increase the percentage surface dose, reduce skin-sparing effect, and protect OAR. The aim of this is to provide an adjustable, transparent, and easily fabricated, less expensive, nontoxic bolus which can be used in the radiotherapy.</abstract><cop>Thailand</cop><pub>West Asia Organization for Cancer Prevention</pub><pmid>36708562</pmid><doi>10.31557/APJCP.2023.24.1.141</doi><tpages>7</tpages><orcidid>https://orcid.org/000000152557212</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2476-762X
ispartof Asian Pacific Journal of Cancer Prevention, 2023-01, Vol.24 (1), p.141-147
issn 2476-762X
1513-7368
2476-762X
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10152843
source MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free E- Journals
subjects Elastomers
Humans
Neoplasms - radiotherapy
Phantoms, Imaging
Photons - therapeutic use
Radiometry
Radiotherapy
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted
Silicone Elastomers
title Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T14%3A42%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Fabrication%20and%20Dosimetric%20Characteristics%20of%20Silicon%20Elastomer-Based%20Bolus%20Using%20External%20Beam%20Radiotherapy&rft.jtitle=Asian%20Pacific%20Journal%20of%20Cancer%20Prevention&rft.au=Boopathi,%20M&rft.date=2023-01-01&rft.volume=24&rft.issue=1&rft.spage=141&rft.epage=147&rft.pages=141-147&rft.issn=2476-762X&rft.eissn=2476-762X&rft_id=info:doi/10.31557/APJCP.2023.24.1.141&rft_dat=%3Cpubmed_cross%3E36708562%3C/pubmed_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/36708562&rfr_iscdi=true