NMDA-receptor-Fc-fusion constructs neutralize anti-NMDA receptor antibodies

Abstract N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most common subtype of autoimmune encephalitis characterized by a complex neuropsychiatric syndrome usually including memory impairment. Patients develop an intrathecal immune response against NMDARs with antibodies that presumably b...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2023-05, Vol.146 (5), p.1812-1820
Hauptverfasser:	Steinke, Stephan, Kirmann, Toni, Loi, Eleonora A, Nerlich, Jana, Weichard, Iron, Kuhn, Philipp, Bullmann, Torsten, Ritzau-Jost, Andreas, Rizalar, Filiz Sila, Prüss, Harald, Haucke, Volker, Geis, Christian, Hust, Michael, Hallermann, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoantibodies - metabolism Encephalitis Hashimoto Disease Humans Induced Pluripotent Stem Cells - metabolism Mice Receptors, N-Methyl-D-Aspartate - metabolism
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