Macrophages in the synovial lining niche initiate neutrophil recruitment and articular inflammation

The first immune-activating changes within joint resident cells that lead to pathogenic leukocyte recruitment during articular inflammation remain largely unknown. In this study, we employ state-of-the-art confocal microscopy and image analysis in a systemic, whole-organ, and quantitative way to pre...

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Veröffentlicht in:	The Journal of experimental medicine 2023-08, Vol.220 (8)
Hauptverfasser:	Zec, Kristina, Schonfeldova, Barbora, Ai, Zhichao, Van Grinsven, Erinke, Pirgova, Gabriela, Eames, Hayley L, Berthold, Dorothée L, Attar, Moustafa, Compeer, Ewoud B, Arnon, Tal I, Udalova, Irina A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Arthritis - pathology Brief Definitive Report Humans Inflammation - pathology Innate Immunity and Inflammation Macrophages Neutrophil Infiltration Synovial Membrane - pathology
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