Oscillation of Autophagy Induction under Cellular Stress and What Lies behind It, a Systems Biology Study

One of the main inducers of autophagy-dependent self-cannibalism, called ULK1, is tightly regulated by the two sensor molecules of nutrient conditions and energy status, known as mTOR and AMPK kinases, respectively. Recently, we developed a freely available mathematical model to explore the oscillat...

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Veröffentlicht in:	International journal of molecular sciences 2023-04, Vol.24 (8), p.7671
Hauptverfasser:	Hajdú, Bence, Csabai, Luca, Márton, Margita, Holczer, Marianna, Korcsmáros, Tamás, Kapuy, Orsolya
Format:	Artikel
Sprache:	eng
Schlagworte:	AMP-Activated Protein Kinases - metabolism Analysis Autophagy Autophagy-Related Protein-1 Homolog - genetics Autophagy-Related Protein-1 Homolog - metabolism Intracellular Signaling Peptides and Proteins - pharmacology Proteins Systems Biology TOR Serine-Threonine Kinases - metabolism Vorinostat
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