Development, Processing and Aging of Novel Zn-Ag-Cu Based Biodegradable Alloys

The use of biodegradable materials for implants is a promising strategy to overcome known long-term clinical complications related to permanent implants. Ideally, biodegradable implants support the damaged tissue for a certain period and then degrade, while the physiological function of the surround...

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Veröffentlicht in:Materials 2023-04, Vol.16 (8), p.3198
Hauptverfasser: Heiss, Alexander, Thatikonda, Venkat Sai, Richter, Andreas, Schmitt, Lisa-Yvonn, Park, Daesung, Klotz, Ulrich E
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container_issue 8
container_start_page 3198
container_title Materials
container_volume 16
creator Heiss, Alexander
Thatikonda, Venkat Sai
Richter, Andreas
Schmitt, Lisa-Yvonn
Park, Daesung
Klotz, Ulrich E
description The use of biodegradable materials for implants is a promising strategy to overcome known long-term clinical complications related to permanent implants. Ideally, biodegradable implants support the damaged tissue for a certain period and then degrade, while the physiological function of the surrounding tissue is restored. Although Mg-based alloys nearly ideally lend themselves to biodegradable implants, a few critical shortcomings promoted the development of alternative alloy systems. Due to their reasonably good biocompatibility, moderate corrosion rate without hydrogen evolution and adequate mechanical properties, increasing attention has been paid to Zn alloys. In this work, precipitation-hardening alloys in the system Zn-Ag-Cu were developed relying on thermodynamic calculations. After casting the alloys, their microstructures were refined by thermomechanical treatment. The processing was tracked and directed, respectively, by routine investigations of the microstructure, associated with hardness assessments. Although microstructure refinement increased the hardness, the material proved to be susceptible to aging as the homologous temperature of zinc is at 0.43 T . Besides mechanical performance and corrosion rate, long-term mechanical stability is another crucial factor that must be taken into consideration to ensure the safety of the implant and thus requires a profound understanding of the aging process.
doi_str_mv 10.3390/ma16083198
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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). 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Although microstructure refinement increased the hardness, the material proved to be susceptible to aging as the homologous temperature of zinc is at 0.43 T . Besides mechanical performance and corrosion rate, long-term mechanical stability is another crucial factor that must be taken into consideration to ensure the safety of the implant and thus requires a profound understanding of the aging process.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>37110036</pmid><doi>10.3390/ma16083198</doi><orcidid>https://orcid.org/0000-0002-6033-6636</orcidid><orcidid>https://orcid.org/0000-0002-5993-4508</orcidid><orcidid>https://orcid.org/0000-0002-6033-1659</orcidid><oa>free_for_read</oa></addata></record>
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source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central; Free Full-Text Journals in Chemistry
subjects Acids
Aging
Aging (metallurgy)
Alloy systems
Alloys
Annealing
Biocompatibility
Biodegradable materials
Casting alloys
Cold
Copper
Corrosion and anti-corrosives
Corrosion potential
Corrosion rate
Deformation
Hardness
Hydrogen evolution
Implants
Investigations
Ion beams
Magnesium base alloys
Mechanical properties
Metals
Microscopy
Microstructure
Orthopedics
Precipitation hardening alloys
Scientific imaging
Silver
Software
Specialty metals industry
Strain hardening
Thermomechanical treatment
Transplants & implants
Zinc
Zinc base alloys
Zinc compounds
title Development, Processing and Aging of Novel Zn-Ag-Cu Based Biodegradable Alloys
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