Double Mutations in a Patient with Early-Onset Alzheimer's Disease in Korea: An APP Val551Met and a PSEN2 His169Asn

The etiology of early-onset Alzheimer's disease (EOAD) is associated with alterations in the production of amyloid beta (Aβ) species caused by mutations in the , , and genes. Mutations affect intra- or inter-molecular interactions and processes between the γ-secretase complex and amyloid precur...

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Veröffentlicht in:	International journal of molecular sciences 2023-04, Vol.24 (8), p.7446
Hauptverfasser:	Bae, Heewon, Shim, Kyu Hwan, Yoo, Jang, Yang, Young-Soon, An, Seong Soo A, Kang, Min-Ju
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - epidemiology Alzheimer Disease - genetics Amyloid beta-Peptides - genetics Amyloid beta-Protein Precursor - genetics Communication Female Humans Middle Aged Mutation Presenilin-1 - genetics Presenilin-2 - genetics Republic of Korea
Online-Zugang:	Volltext
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