$Bioactive fraction from Plumeria obtusa L. attenuates LPS-induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF-MS and molecular docking$

Bioactive fraction from Plumeria obtusa L. attenuates LPS-induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF-MS and molecular docking

In this study, the anti-inflammatory effects of the methanolic extract (TE) of Plumeria obtusa L. (aerial parts) and its fractions were evaluated in vitro, and active fraction was evaluated in vivo. Among tested extracts, dichloromethane fraction (DCM-F) exhibited the strongest inhibition of lipopol...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Inflammopharmacology 2023-04, Vol.31 (2), p.859-875
Hauptverfasser:	Eloutify, Yousra T., El-Shiekh, Riham A., Ibrahim, Khaled Meselhy, Hamed, Ahmed R., Al-Karmalawy, Ahmed A., Shokry, Aya A., Ahmed, Yasmine H., Avula, Bharathi, Katragunta, Kumar, Khan, Ikhlas A., Meselhy, Meselhy R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Lung Injury - chemically induced Acute Lung Injury - drug therapy Acute Lung Injury - metabolism Allergology Animals Anti-Inflammatory Agents - therapeutic use Biomedical and Life Sciences Biomedicine Dermatology Gastroenterology Immunology Inflammation - metabolism Lipopolysaccharides - pharmacology Macrophages Mice Molecular Docking Simulation NF-kappa B - metabolism Nitric Oxide - metabolism Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type II - metabolism Original Original Article Pharmacology/Toxicology Plant Extracts - therapeutic use Rheumatology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!