Immobilization of M3 Muscarinic Receptor to Rapidly Analyze Drug-Protein Interactions and Bioactive Components in a Natural Plant

Despite its increasing application in pursing potential ligands, the capacity of receptor affinity chromatography is greatly challenged as most current research studies lack a comprehensive characterization of the ligand-receptor interaction, particularly when simultaneously determining their bindin...

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Veröffentlicht in:	International journal of molecular sciences 2023-04, Vol.24 (8), p.7171
Hauptverfasser:	Fan, Hushuai, Huang, Xiaomin, Zhang, Ziru, Wang, Ting, Wang, Ludan, Zhang, Yajun
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular signal transduction Chromatography Drug discovery Hyoscyamine Pilocarpine Plant Extracts - pharmacology Protein binding Receptor, Muscarinic M3 - metabolism Scopolamine Derivatives Tiotropium Valsartan
Online-Zugang:	Volltext
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