Salvage Surgery for Small-Cell Lung Cancer-A Literature Review

(1) Background: Salvation surgery for small-cell lung cancer (SCLC) is exceptionally performed, and only a few cases are published. (2) Methods: There are 6 publications that present 17 cases of salvation surgery for SCLC-the salvation surgery was performed in the context of modern clearly establish...

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Veröffentlicht in:Cancers 2023-04, Vol.15 (8), p.2241
Hauptverfasser: Motas, Natalia, Manolache, Veronica, Scarci, Marco, Nimigean, Victor, Nimigean, Vanda Roxana, Simion, Laurentiu, Mizea, Madalina Cristiana, Trifanescu, Oana Gabriela, Galateanu, Bianca, Gherghe, Mirela, Capsa, Cristina Mirela, Gonzalez-Rivas, Diego, Davidescu, Mihnea Dan
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Sprache:eng
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Zusammenfassung:(1) Background: Salvation surgery for small-cell lung cancer (SCLC) is exceptionally performed, and only a few cases are published. (2) Methods: There are 6 publications that present 17 cases of salvation surgery for SCLC-the salvation surgery was performed in the context of modern clearly established protocols for SCLC and after including SCLC in the TNM (tumor, node, metastasis) staging in 2010. (3) Results: After a median follow-up of 29 months, the estimated overall survival (OS) was 86 months. The median estimated 2-year survival was 92%, and the median estimated 5-year survival was 66%. (4) Conclusion: Salvage surgery for SCLC is a relatively new and extremely uncommon concept and represents an alternative to second-line chemotherapy. It is valuable because it may offer a reasonable treatment for selected patients, good local control, and a favorable survival outcome.
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers15082241