Association of Trauma Molecular Endotypes With Differential Response to Transfusion Resuscitation Strategies

IMPORTANCE: It is not clear which severely injured patients with hemorrhagic shock may benefit most from a 1:1:1 vs 1:1:2 (plasma:platelets:red blood cells) resuscitation strategy. Identification of trauma molecular endotypes may reveal subgroups of patients with differential treatment response to v...

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Veröffentlicht in:	Archives of surgery (Chicago. 1960) 2023-07, Vol.158 (7), p.728-736
Hauptverfasser:	Thau, Matthew R, Liu, Ted, Sathe, Neha A, O’Keefe, Grant E, Robinson, Bryce R. H, Bulger, Eileen, Wade, Charles E, Fox, Erin E, Holcomb, John B, Liles, W. Conrad, Stanaway, Ian B, Mikacenic, Carmen, Wurfel, Mark M, Bhatraju, Pavan K, Morrell, Eric D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers Blood Transfusion Clinical outcomes Hemorrhagic shock Hemostatics Humans Injury Severity Score Male Mortality Online First Original Investigation Resuscitation - methods Shock, Hemorrhagic - therapy
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