Factors associated with poor outcomes in patients with severe acute respiratory infections in Bahrain
Background Severe acute respiratory tract infection (SARI) is a major global health threat. This study aimed to examine risk factors associated with poor outcomes in patients with SARI. Methods All patients who met World Health Organization's (WHO) SARI case definition and were admitted to Salm...
Gespeichert in:
| Veröffentlicht in: | Influenza and other respiratory viruses 2023-04, Vol.17 (4), p.e13133-n/a |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | n/a |
|---|---|
| container_issue | 4 |
| container_start_page | e13133 |
| container_title | Influenza and other respiratory viruses |
| container_volume | 17 |
| creator | Mohamed, Afaf Merza Al Sayyad, Adel Matar, Ebrahim Isa, Hasan M. Hasan, Wafa Fawzi Hashim, Nawra Sayed Jalal Yusuf Alajaimi, Bayan Abduljalil Aldolabi, Qatrmeer |
| description | Background
Severe acute respiratory tract infection (SARI) is a major global health threat. This study aimed to examine risk factors associated with poor outcomes in patients with SARI.
Methods
All patients who met World Health Organization's (WHO) SARI case definition and were admitted to Salmaniya Medical Complex from January 2018 to December 2021 were included. Epidemiological and virological data were obtained and analyzed.
Results
Of 1159 patients with SARI included, 731 (63.1%) patients were below 50 years, and 357 (30.8%) tested positive for viral pathogens. The most prevalent virus was Flu‐A (n = 134, 37.5%), SARS‐CoV2 (n = 118, 33%), RSV (n = 51, 14.3%), Flu B (n = 49,13.7%), other viruses (n = 3, 0.8%), and combined infection (n = 2, 0.6%). Six hundred fifty‐eight (56.8%) patients had comorbidities, mainly diabetes (n = 284, 43%) and heart disease (n = 217, 33%). 183 (16%) patients were admitted to ICU, 110 (9%) needed mechanical ventilation, and 80 (7%) patients died.
The odds of ICU admission were higher for patients with hematological (OR 5.9, 95% CI 3.1–11.1) and lung diseases (OR 2.7, 95% CI 1.6–4.6). The odds of mechanical ventilation were higher among patients with lung disease (OR 3.1, 95% 1.7–5.5). The mortality odds were higher among patients above 50 (OR 2.4, 95% CI 1.4–4.1) and chronic kidney disease (OR 2.5, 95% CI 1.1–5.2).
Conclusions
Being 50 years or above or having kidney, lung, or heart diseases was associated with worse SARI outcomes. Efforts and actions in developing better strategies to vaccinate individuals at high risk and early diagnosis and treatment should help in reducing the burden of SARI. |
| doi_str_mv | 10.1111/irv.13133 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10133729</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2808082025</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4443-6cf49e3cea4464ddfab82f1aca3d95439a722ffd3a450d3f1b5cb67cd6ef72c53</originalsourceid><addsrcrecordid>eNp1kUtLJDEURoOM-F74B4aC2eiiNa96rURlnBEEQdRtuJ26sSPVlZok1dL_fmKXNiqYTQL35PAlHyGHjJ6wtE6tX5wwwYTYIDuszOmEF3n9Y32WdJvshvBMaV5Uudwi26JkXFRM7BC8Ah2dDxmE4LSFiE32YuMs653zmRuidnMMme2yHqLFLoZxHHCBHjPQQ8TMY-ith-RZJtKgjtZ1q0sXMPNgu32yaaANePC275GHq9_3l38nN7d_ri_PbyZaSikmhTayRqERpCxk0xiYVtww0CCaOpeihpJzYxoBMqeNMGya62lR6qZAU3Kdiz1yNnr7YTrHRqe8HlrVezsHv1QOrPo86exMPbmFYjT9XsnrZDh6M3j3b8AQ1dwGjW0LHbohKF7RijNecpnQX1_QZzf4Lr1vRSWO8tdIxyOlvQvBo1mnYVS9tqdSe2rVXmJ_foy_Jt_rSsDpCLzYFpffm9T13eOo_A8xaKcf</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2808082025</pqid></control><display><type>article</type><title>Factors associated with poor outcomes in patients with severe acute respiratory infections in Bahrain</title><source>MEDLINE</source><source>Wiley Online Library Open Access</source><source>DOAJ Directory of Open Access Journals</source><source>Wiley Online Library Journals Frontfile Complete</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Mohamed, Afaf Merza ; Al Sayyad, Adel ; Matar, Ebrahim ; Isa, Hasan M. ; Hasan, Wafa Fawzi ; Hashim, Nawra Sayed Jalal Yusuf ; Alajaimi, Bayan Abduljalil ; Aldolabi, Qatrmeer</creator><creatorcontrib>Mohamed, Afaf Merza ; Al Sayyad, Adel ; Matar, Ebrahim ; Isa, Hasan M. ; Hasan, Wafa Fawzi ; Hashim, Nawra Sayed Jalal Yusuf ; Alajaimi, Bayan Abduljalil ; Aldolabi, Qatrmeer</creatorcontrib><description>Background
Severe acute respiratory tract infection (SARI) is a major global health threat. This study aimed to examine risk factors associated with poor outcomes in patients with SARI.
Methods
All patients who met World Health Organization's (WHO) SARI case definition and were admitted to Salmaniya Medical Complex from January 2018 to December 2021 were included. Epidemiological and virological data were obtained and analyzed.
Results
Of 1159 patients with SARI included, 731 (63.1%) patients were below 50 years, and 357 (30.8%) tested positive for viral pathogens. The most prevalent virus was Flu‐A (n = 134, 37.5%), SARS‐CoV2 (n = 118, 33%), RSV (n = 51, 14.3%), Flu B (n = 49,13.7%), other viruses (n = 3, 0.8%), and combined infection (n = 2, 0.6%). Six hundred fifty‐eight (56.8%) patients had comorbidities, mainly diabetes (n = 284, 43%) and heart disease (n = 217, 33%). 183 (16%) patients were admitted to ICU, 110 (9%) needed mechanical ventilation, and 80 (7%) patients died.
The odds of ICU admission were higher for patients with hematological (OR 5.9, 95% CI 3.1–11.1) and lung diseases (OR 2.7, 95% CI 1.6–4.6). The odds of mechanical ventilation were higher among patients with lung disease (OR 3.1, 95% 1.7–5.5). The mortality odds were higher among patients above 50 (OR 2.4, 95% CI 1.4–4.1) and chronic kidney disease (OR 2.5, 95% CI 1.1–5.2).
Conclusions
Being 50 years or above or having kidney, lung, or heart diseases was associated with worse SARI outcomes. Efforts and actions in developing better strategies to vaccinate individuals at high risk and early diagnosis and treatment should help in reducing the burden of SARI.</description><identifier>ISSN: 1750-2640</identifier><identifier>ISSN: 1750-2659</identifier><identifier>EISSN: 1750-2659</identifier><identifier>DOI: 10.1111/irv.13133</identifier><identifier>PMID: 37123813</identifier><language>eng</language><publisher>England: John Wiley & Sons, Inc</publisher><subject>Age groups ; Bahrain ; Bahrain - epidemiology ; Cardiovascular disease ; Cardiovascular diseases ; Comorbidity ; Coronaviruses ; COVID-19 ; Diabetes ; Diabetes mellitus ; Epidemiology ; Global health ; Health risks ; Heart ; Heart diseases ; Hematology ; Hospitalization ; Hospitals ; Humans ; Immunization ; Infant ; Infections ; Influenza ; Influenza, Human ; Kidney diseases ; Kidneys ; Laboratories ; Lung diseases ; Mechanical ventilation ; Mortality ; Original ; outcome ; Pandemics ; Pathogens ; Patients ; Public health ; Regression analysis ; Respiratory diseases ; respiratory infections ; Respiratory tract ; Respiratory tract diseases ; Respiratory tract infection ; Respiratory Tract Infections - epidemiology ; Risk factors ; RNA, Viral ; SARI ; SARS-CoV-2 ; Severe acute respiratory syndrome coronavirus 2 ; Statistical analysis ; Vaccines ; Ventilation ; Ventilators ; Viral diseases ; Viruses</subject><ispartof>Influenza and other respiratory viruses, 2023-04, Vol.17 (4), p.e13133-n/a</ispartof><rights>2023 The Authors. published by John Wiley & Sons Ltd.</rights><rights>2023 The Authors. Influenza and Other Respiratory Viruses published by John Wiley & Sons Ltd.</rights><rights>2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4443-6cf49e3cea4464ddfab82f1aca3d95439a722ffd3a450d3f1b5cb67cd6ef72c53</citedby><cites>FETCH-LOGICAL-c4443-6cf49e3cea4464ddfab82f1aca3d95439a722ffd3a450d3f1b5cb67cd6ef72c53</cites><orcidid>0000-0002-5995-6838 ; 0000-0003-2376-8998 ; 0000-0002-8552-3980 ; 0000-0001-5983-3793 ; 0000-0001-6022-5576 ; 0000-0002-2200-3734</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133729/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133729/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,1411,11541,27901,27902,45550,45551,46027,46451,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37123813$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mohamed, Afaf Merza</creatorcontrib><creatorcontrib>Al Sayyad, Adel</creatorcontrib><creatorcontrib>Matar, Ebrahim</creatorcontrib><creatorcontrib>Isa, Hasan M.</creatorcontrib><creatorcontrib>Hasan, Wafa Fawzi</creatorcontrib><creatorcontrib>Hashim, Nawra Sayed Jalal Yusuf</creatorcontrib><creatorcontrib>Alajaimi, Bayan Abduljalil</creatorcontrib><creatorcontrib>Aldolabi, Qatrmeer</creatorcontrib><title>Factors associated with poor outcomes in patients with severe acute respiratory infections in Bahrain</title><title>Influenza and other respiratory viruses</title><addtitle>Influenza Other Respir Viruses</addtitle><description>Background
Severe acute respiratory tract infection (SARI) is a major global health threat. This study aimed to examine risk factors associated with poor outcomes in patients with SARI.
Methods
All patients who met World Health Organization's (WHO) SARI case definition and were admitted to Salmaniya Medical Complex from January 2018 to December 2021 were included. Epidemiological and virological data were obtained and analyzed.
Results
Of 1159 patients with SARI included, 731 (63.1%) patients were below 50 years, and 357 (30.8%) tested positive for viral pathogens. The most prevalent virus was Flu‐A (n = 134, 37.5%), SARS‐CoV2 (n = 118, 33%), RSV (n = 51, 14.3%), Flu B (n = 49,13.7%), other viruses (n = 3, 0.8%), and combined infection (n = 2, 0.6%). Six hundred fifty‐eight (56.8%) patients had comorbidities, mainly diabetes (n = 284, 43%) and heart disease (n = 217, 33%). 183 (16%) patients were admitted to ICU, 110 (9%) needed mechanical ventilation, and 80 (7%) patients died.
The odds of ICU admission were higher for patients with hematological (OR 5.9, 95% CI 3.1–11.1) and lung diseases (OR 2.7, 95% CI 1.6–4.6). The odds of mechanical ventilation were higher among patients with lung disease (OR 3.1, 95% 1.7–5.5). The mortality odds were higher among patients above 50 (OR 2.4, 95% CI 1.4–4.1) and chronic kidney disease (OR 2.5, 95% CI 1.1–5.2).
Conclusions
Being 50 years or above or having kidney, lung, or heart diseases was associated with worse SARI outcomes. Efforts and actions in developing better strategies to vaccinate individuals at high risk and early diagnosis and treatment should help in reducing the burden of SARI.</description><subject>Age groups</subject><subject>Bahrain</subject><subject>Bahrain - epidemiology</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular diseases</subject><subject>Comorbidity</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Epidemiology</subject><subject>Global health</subject><subject>Health risks</subject><subject>Heart</subject><subject>Heart diseases</subject><subject>Hematology</subject><subject>Hospitalization</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Immunization</subject><subject>Infant</subject><subject>Infections</subject><subject>Influenza</subject><subject>Influenza, Human</subject><subject>Kidney diseases</subject><subject>Kidneys</subject><subject>Laboratories</subject><subject>Lung diseases</subject><subject>Mechanical ventilation</subject><subject>Mortality</subject><subject>Original</subject><subject>outcome</subject><subject>Pandemics</subject><subject>Pathogens</subject><subject>Patients</subject><subject>Public health</subject><subject>Regression analysis</subject><subject>Respiratory diseases</subject><subject>respiratory infections</subject><subject>Respiratory tract</subject><subject>Respiratory tract diseases</subject><subject>Respiratory tract infection</subject><subject>Respiratory Tract Infections - epidemiology</subject><subject>Risk factors</subject><subject>RNA, Viral</subject><subject>SARI</subject><subject>SARS-CoV-2</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>Statistical analysis</subject><subject>Vaccines</subject><subject>Ventilation</subject><subject>Ventilators</subject><subject>Viral diseases</subject><subject>Viruses</subject><issn>1750-2640</issn><issn>1750-2659</issn><issn>1750-2659</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kUtLJDEURoOM-F74B4aC2eiiNa96rURlnBEEQdRtuJ26sSPVlZok1dL_fmKXNiqYTQL35PAlHyGHjJ6wtE6tX5wwwYTYIDuszOmEF3n9Y32WdJvshvBMaV5Uudwi26JkXFRM7BC8Ah2dDxmE4LSFiE32YuMs653zmRuidnMMme2yHqLFLoZxHHCBHjPQQ8TMY-ith-RZJtKgjtZ1q0sXMPNgu32yaaANePC275GHq9_3l38nN7d_ri_PbyZaSikmhTayRqERpCxk0xiYVtww0CCaOpeihpJzYxoBMqeNMGya62lR6qZAU3Kdiz1yNnr7YTrHRqe8HlrVezsHv1QOrPo86exMPbmFYjT9XsnrZDh6M3j3b8AQ1dwGjW0LHbohKF7RijNecpnQX1_QZzf4Lr1vRSWO8tdIxyOlvQvBo1mnYVS9tqdSe2rVXmJ_foy_Jt_rSsDpCLzYFpffm9T13eOo_A8xaKcf</recordid><startdate>202304</startdate><enddate>202304</enddate><creator>Mohamed, Afaf Merza</creator><creator>Al Sayyad, Adel</creator><creator>Matar, Ebrahim</creator><creator>Isa, Hasan M.</creator><creator>Hasan, Wafa Fawzi</creator><creator>Hashim, Nawra Sayed Jalal Yusuf</creator><creator>Alajaimi, Bayan Abduljalil</creator><creator>Aldolabi, Qatrmeer</creator><general>John Wiley & Sons, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T2</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-5995-6838</orcidid><orcidid>https://orcid.org/0000-0003-2376-8998</orcidid><orcidid>https://orcid.org/0000-0002-8552-3980</orcidid><orcidid>https://orcid.org/0000-0001-5983-3793</orcidid><orcidid>https://orcid.org/0000-0001-6022-5576</orcidid><orcidid>https://orcid.org/0000-0002-2200-3734</orcidid></search><sort><creationdate>202304</creationdate><title>Factors associated with poor outcomes in patients with severe acute respiratory infections in Bahrain</title><author>Mohamed, Afaf Merza ; Al Sayyad, Adel ; Matar, Ebrahim ; Isa, Hasan M. ; Hasan, Wafa Fawzi ; Hashim, Nawra Sayed Jalal Yusuf ; Alajaimi, Bayan Abduljalil ; Aldolabi, Qatrmeer</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4443-6cf49e3cea4464ddfab82f1aca3d95439a722ffd3a450d3f1b5cb67cd6ef72c53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Age groups</topic><topic>Bahrain</topic><topic>Bahrain - epidemiology</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular diseases</topic><topic>Comorbidity</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Epidemiology</topic><topic>Global health</topic><topic>Health risks</topic><topic>Heart</topic><topic>Heart diseases</topic><topic>Hematology</topic><topic>Hospitalization</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Immunization</topic><topic>Infant</topic><topic>Infections</topic><topic>Influenza</topic><topic>Influenza, Human</topic><topic>Kidney diseases</topic><topic>Kidneys</topic><topic>Laboratories</topic><topic>Lung diseases</topic><topic>Mechanical ventilation</topic><topic>Mortality</topic><topic>Original</topic><topic>outcome</topic><topic>Pandemics</topic><topic>Pathogens</topic><topic>Patients</topic><topic>Public health</topic><topic>Regression analysis</topic><topic>Respiratory diseases</topic><topic>respiratory infections</topic><topic>Respiratory tract</topic><topic>Respiratory tract diseases</topic><topic>Respiratory tract infection</topic><topic>Respiratory Tract Infections - epidemiology</topic><topic>Risk factors</topic><topic>RNA, Viral</topic><topic>SARI</topic><topic>SARS-CoV-2</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><topic>Statistical analysis</topic><topic>Vaccines</topic><topic>Ventilation</topic><topic>Ventilators</topic><topic>Viral diseases</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mohamed, Afaf Merza</creatorcontrib><creatorcontrib>Al Sayyad, Adel</creatorcontrib><creatorcontrib>Matar, Ebrahim</creatorcontrib><creatorcontrib>Isa, Hasan M.</creatorcontrib><creatorcontrib>Hasan, Wafa Fawzi</creatorcontrib><creatorcontrib>Hashim, Nawra Sayed Jalal Yusuf</creatorcontrib><creatorcontrib>Alajaimi, Bayan Abduljalil</creatorcontrib><creatorcontrib>Aldolabi, Qatrmeer</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Influenza and other respiratory viruses</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mohamed, Afaf Merza</au><au>Al Sayyad, Adel</au><au>Matar, Ebrahim</au><au>Isa, Hasan M.</au><au>Hasan, Wafa Fawzi</au><au>Hashim, Nawra Sayed Jalal Yusuf</au><au>Alajaimi, Bayan Abduljalil</au><au>Aldolabi, Qatrmeer</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors associated with poor outcomes in patients with severe acute respiratory infections in Bahrain</atitle><jtitle>Influenza and other respiratory viruses</jtitle><addtitle>Influenza Other Respir Viruses</addtitle><date>2023-04</date><risdate>2023</risdate><volume>17</volume><issue>4</issue><spage>e13133</spage><epage>n/a</epage><pages>e13133-n/a</pages><issn>1750-2640</issn><issn>1750-2659</issn><eissn>1750-2659</eissn><abstract>Background
Severe acute respiratory tract infection (SARI) is a major global health threat. This study aimed to examine risk factors associated with poor outcomes in patients with SARI.
Methods
All patients who met World Health Organization's (WHO) SARI case definition and were admitted to Salmaniya Medical Complex from January 2018 to December 2021 were included. Epidemiological and virological data were obtained and analyzed.
Results
Of 1159 patients with SARI included, 731 (63.1%) patients were below 50 years, and 357 (30.8%) tested positive for viral pathogens. The most prevalent virus was Flu‐A (n = 134, 37.5%), SARS‐CoV2 (n = 118, 33%), RSV (n = 51, 14.3%), Flu B (n = 49,13.7%), other viruses (n = 3, 0.8%), and combined infection (n = 2, 0.6%). Six hundred fifty‐eight (56.8%) patients had comorbidities, mainly diabetes (n = 284, 43%) and heart disease (n = 217, 33%). 183 (16%) patients were admitted to ICU, 110 (9%) needed mechanical ventilation, and 80 (7%) patients died.
The odds of ICU admission were higher for patients with hematological (OR 5.9, 95% CI 3.1–11.1) and lung diseases (OR 2.7, 95% CI 1.6–4.6). The odds of mechanical ventilation were higher among patients with lung disease (OR 3.1, 95% 1.7–5.5). The mortality odds were higher among patients above 50 (OR 2.4, 95% CI 1.4–4.1) and chronic kidney disease (OR 2.5, 95% CI 1.1–5.2).
Conclusions
Being 50 years or above or having kidney, lung, or heart diseases was associated with worse SARI outcomes. Efforts and actions in developing better strategies to vaccinate individuals at high risk and early diagnosis and treatment should help in reducing the burden of SARI.</abstract><cop>England</cop><pub>John Wiley & Sons, Inc</pub><pmid>37123813</pmid><doi>10.1111/irv.13133</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-5995-6838</orcidid><orcidid>https://orcid.org/0000-0003-2376-8998</orcidid><orcidid>https://orcid.org/0000-0002-8552-3980</orcidid><orcidid>https://orcid.org/0000-0001-5983-3793</orcidid><orcidid>https://orcid.org/0000-0001-6022-5576</orcidid><orcidid>https://orcid.org/0000-0002-2200-3734</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1750-2640 |
| ispartof | Influenza and other respiratory viruses, 2023-04, Vol.17 (4), p.e13133-n/a |
| issn | 1750-2640 1750-2659 1750-2659 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10133729 |
| source | MEDLINE; Wiley Online Library Open Access; DOAJ Directory of Open Access Journals; Wiley Online Library Journals Frontfile Complete; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Age groups Bahrain Bahrain - epidemiology Cardiovascular disease Cardiovascular diseases Comorbidity Coronaviruses COVID-19 Diabetes Diabetes mellitus Epidemiology Global health Health risks Heart Heart diseases Hematology Hospitalization Hospitals Humans Immunization Infant Infections Influenza Influenza, Human Kidney diseases Kidneys Laboratories Lung diseases Mechanical ventilation Mortality Original outcome Pandemics Pathogens Patients Public health Regression analysis Respiratory diseases respiratory infections Respiratory tract Respiratory tract diseases Respiratory tract infection Respiratory Tract Infections - epidemiology Risk factors RNA, Viral SARI SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Statistical analysis Vaccines Ventilation Ventilators Viral diseases Viruses |
| title | Factors associated with poor outcomes in patients with severe acute respiratory infections in Bahrain |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T17%3A21%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Factors%20associated%20with%20poor%20outcomes%20in%20patients%20with%20severe%20acute%20respiratory%20infections%20in%20Bahrain&rft.jtitle=Influenza%20and%20other%20respiratory%20viruses&rft.au=Mohamed,%20Afaf%20Merza&rft.date=2023-04&rft.volume=17&rft.issue=4&rft.spage=e13133&rft.epage=n/a&rft.pages=e13133-n/a&rft.issn=1750-2640&rft.eissn=1750-2659&rft_id=info:doi/10.1111/irv.13133&rft_dat=%3Cproquest_pubme%3E2808082025%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2808082025&rft_id=info:pmid/37123813&rfr_iscdi=true |