Characterization and Amelioration of Filtration Difficulties Encountered in Metabolomic Studies of Clostridium thermocellum at Elevated Sugar Concentrations

Clostridium thermocellum, a promising candidate for consolidated bioprocessing, has been subjected to numerous engineering strategies for enhanced bioethanol production. Measurements of intracellular metabolites at substrate concentrations high enough (>50 g/L) to allow the production of industri...

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Veröffentlicht in:	Applied and environmental microbiology 2023-04, Vol.89 (4), p.e0040623-e0040623
Hauptverfasser:	Sharma, Bishal D, Olson, Daniel G, Giannone, Richard J, Hettich, Robert L, Lynd, Lee R
Format:	Artikel
Sprache:	eng
Schlagworte:	Active control Bacteria BASIC BIOLOGICAL SCIENCES Biofuels Bioprocessing Biotechnology Clostridium thermocellum Clostridium thermocellum - metabolism E coli Ethanol Ethanol - metabolism exopolysaccharide extracellular polymeric substance Filtration Intracellular Metabolic Engineering Metabolites Metabolomics pH control Substrates Sugars - metabolism viscosity
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