Understanding a protein fold: The physics, chemistry, and biology of α-helical coiled coils

Protein science is being transformed by powerful computational methods for structure prediction and design: AlphaFold2 can predict many natural protein structures from sequence, and other AI methods are enabling the de novo design of new structures. This raises a question: how much do we understand...

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Veröffentlicht in:	The Journal of biological chemistry 2023-04, Vol.299 (4), p.104579-104579, Article 104579
1. Verfasser:	Woolfson, Derek N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology coiled coil JBC Reviews peptide assembly Physics Protein Conformation, alpha-Helical protein design Protein Domains Protein Folding Proteins - chemistry Proteins - metabolism quaternary structure structural biology α helix
Online-Zugang:	Volltext
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