An extremely rare case of an isolated primary benign pelvic Solitary Fibrous Tumor in an elderly female
Solitary Fibrous Tumors are highly rare spindle cell tumors of mesenchymal origin. They comprise
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| Veröffentlicht in: | International journal of surgery case reports 2023-05, Vol.106, p.108168, Article 108168 |
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| container_title | International journal of surgery case reports |
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| creator | Shaheen, Jack Al Laham, Omar Hokouk, Bashir |
| description | Solitary Fibrous Tumors are highly rare spindle cell tumors of mesenchymal origin. They comprise |
| doi_str_mv | 10.1016/j.ijscr.2023.108168 |
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We present the case of a 67-year-old female who has a known history of controlled hypertension, who presented to our hospital complaining of non-specific pain in her right flank and lower lumbar region. Our preoperative diagnostic radiological workup demonstrated an isolated antero-sacral mass.
Comprehensive excision of the mass was laparoscopically achieved. Following the necessary analysis via histopathology and immunohistochemistry, we definitively established the diagnosis of an isolated primary benign Solitary Fibrous Tumor.
To the best of our knowledge, no previous cases of SFTs from our country were documented. Clinical suspicion and complete surgical resection are vital determinants in treatment of such patients. Further research and documentation are warranted to set-up the necessary guidelines for preoperative assessment, intraoperative techniques, and adequate follow-up protocols to limit the ensuing morbidity and to detect any possible neoplastic recurrence.
•Solitary Fibrous Tumors are extremely rare spindle cell tumors of mesenchymal origin.•SFTs are <2 % of all soft tissue tumors and have an annual incidence of 0.61 per 1 million cases for extra-meningeal SFTs.•Preoperative radiological analysis shows no specific features. Histopathology defines the definitive diagnosis.•The treatment of choice for SFTs is complete surgical resection of the tumor with adequate free margins.•The 5-year patient survival rate ranges from 59-to-100 %, whereas local recurrence is estimated to reach 8 % for benign SFTs.</description><identifier>ISSN: 2210-2612</identifier><identifier>EISSN: 2210-2612</identifier><identifier>DOI: 10.1016/j.ijscr.2023.108168</identifier><identifier>PMID: 37058810</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Abdominal Surgery ; Case Report ; Pelvic Mass ; Solitary Fibrous Tumor ; Surgical Oncology</subject><ispartof>International journal of surgery case reports, 2023-05, Vol.106, p.108168, Article 108168</ispartof><rights>2023 The Authors</rights><rights>Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.</rights><rights>2023 The Authors 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c377t-6baee0b8147a1b04b77f0f85312b4c31181b65b5a0bca5e9bfadc6abe3a73e33</cites><orcidid>0000-0002-0292-0287</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123260/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ijscr.2023.108168$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,3550,27924,27925,45995,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37058810$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shaheen, Jack</creatorcontrib><creatorcontrib>Al Laham, Omar</creatorcontrib><creatorcontrib>Hokouk, Bashir</creatorcontrib><title>An extremely rare case of an isolated primary benign pelvic Solitary Fibrous Tumor in an elderly female</title><title>International journal of surgery case reports</title><addtitle>Int J Surg Case Rep</addtitle><description>Solitary Fibrous Tumors are highly rare spindle cell tumors of mesenchymal origin. They comprise <2 % of all types of soft tissue tumors and are characterized by an age-adjusted annual incidence rate of 0.61 per 1 million individuals for extra-meningeal Solitary Fibrous Tumors. The disease course is mostly asymptomatic but can still present with non-specific symptoms. This results in misdiagnosis and delayed treatment. In turn, morbidity and mortality rises and it will constitute a clinical and surgical burden for the affected patients.
We present the case of a 67-year-old female who has a known history of controlled hypertension, who presented to our hospital complaining of non-specific pain in her right flank and lower lumbar region. Our preoperative diagnostic radiological workup demonstrated an isolated antero-sacral mass.
Comprehensive excision of the mass was laparoscopically achieved. Following the necessary analysis via histopathology and immunohistochemistry, we definitively established the diagnosis of an isolated primary benign Solitary Fibrous Tumor.
To the best of our knowledge, no previous cases of SFTs from our country were documented. Clinical suspicion and complete surgical resection are vital determinants in treatment of such patients. Further research and documentation are warranted to set-up the necessary guidelines for preoperative assessment, intraoperative techniques, and adequate follow-up protocols to limit the ensuing morbidity and to detect any possible neoplastic recurrence.
•Solitary Fibrous Tumors are extremely rare spindle cell tumors of mesenchymal origin.•SFTs are <2 % of all soft tissue tumors and have an annual incidence of 0.61 per 1 million cases for extra-meningeal SFTs.•Preoperative radiological analysis shows no specific features. Histopathology defines the definitive diagnosis.•The treatment of choice for SFTs is complete surgical resection of the tumor with adequate free margins.•The 5-year patient survival rate ranges from 59-to-100 %, whereas local recurrence is estimated to reach 8 % for benign SFTs.</description><subject>Abdominal Surgery</subject><subject>Case Report</subject><subject>Pelvic Mass</subject><subject>Solitary Fibrous Tumor</subject><subject>Surgical Oncology</subject><issn>2210-2612</issn><issn>2210-2612</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9kN9KwzAUxoMobsw9gSB5gc38WdN6ITKGU2HghbsPSXo6U9pmJN1wb29q55g35ibh5Pu-c84PoVtKppRQcV9ObRmMnzLCeKxkVGQXaMgYJRMmKLs8ew_QOISSxMNZJhi7RgOekiTLKBmizbzB8NV6qKE6YK88YKMCYFdg1WAbXKVayPHW21r5A9bQ2E2Dt1DtrcEfrrJtV15a7d0u4PWudh7bpvNClYOPmQXUqoIbdFWoKsD4eI_Qevm8XrxOVu8vb4v5amJ4mrYToRUA0RmdpYpqMtNpWpAiSzhlemY4pRnVItGJItqoBB50oXIjlAauUg6cj9BTH7vd6RpyA03rVSWP40unrPz709hPuXF7GaEyzgSJCbxPMN6F4KE4mSnpVEKW8ge97NDLHn103Z33PXl-QUfBYy-AuPzegpfBWGgM5NaDaWXu7L8NvgFqEJi4</recordid><startdate>20230501</startdate><enddate>20230501</enddate><creator>Shaheen, Jack</creator><creator>Al Laham, Omar</creator><creator>Hokouk, Bashir</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-0292-0287</orcidid></search><sort><creationdate>20230501</creationdate><title>An extremely rare case of an isolated primary benign pelvic Solitary Fibrous Tumor in an elderly female</title><author>Shaheen, Jack ; Al Laham, Omar ; Hokouk, Bashir</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c377t-6baee0b8147a1b04b77f0f85312b4c31181b65b5a0bca5e9bfadc6abe3a73e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Abdominal Surgery</topic><topic>Case Report</topic><topic>Pelvic Mass</topic><topic>Solitary Fibrous Tumor</topic><topic>Surgical Oncology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shaheen, Jack</creatorcontrib><creatorcontrib>Al Laham, Omar</creatorcontrib><creatorcontrib>Hokouk, Bashir</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of surgery case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shaheen, Jack</au><au>Al Laham, Omar</au><au>Hokouk, Bashir</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An extremely rare case of an isolated primary benign pelvic Solitary Fibrous Tumor in an elderly female</atitle><jtitle>International journal of surgery case reports</jtitle><addtitle>Int J Surg Case Rep</addtitle><date>2023-05-01</date><risdate>2023</risdate><volume>106</volume><spage>108168</spage><pages>108168-</pages><artnum>108168</artnum><issn>2210-2612</issn><eissn>2210-2612</eissn><abstract>Solitary Fibrous Tumors are highly rare spindle cell tumors of mesenchymal origin. They comprise <2 % of all types of soft tissue tumors and are characterized by an age-adjusted annual incidence rate of 0.61 per 1 million individuals for extra-meningeal Solitary Fibrous Tumors. The disease course is mostly asymptomatic but can still present with non-specific symptoms. This results in misdiagnosis and delayed treatment. In turn, morbidity and mortality rises and it will constitute a clinical and surgical burden for the affected patients.
We present the case of a 67-year-old female who has a known history of controlled hypertension, who presented to our hospital complaining of non-specific pain in her right flank and lower lumbar region. Our preoperative diagnostic radiological workup demonstrated an isolated antero-sacral mass.
Comprehensive excision of the mass was laparoscopically achieved. Following the necessary analysis via histopathology and immunohistochemistry, we definitively established the diagnosis of an isolated primary benign Solitary Fibrous Tumor.
To the best of our knowledge, no previous cases of SFTs from our country were documented. Clinical suspicion and complete surgical resection are vital determinants in treatment of such patients. Further research and documentation are warranted to set-up the necessary guidelines for preoperative assessment, intraoperative techniques, and adequate follow-up protocols to limit the ensuing morbidity and to detect any possible neoplastic recurrence.
•Solitary Fibrous Tumors are extremely rare spindle cell tumors of mesenchymal origin.•SFTs are <2 % of all soft tissue tumors and have an annual incidence of 0.61 per 1 million cases for extra-meningeal SFTs.•Preoperative radiological analysis shows no specific features. Histopathology defines the definitive diagnosis.•The treatment of choice for SFTs is complete surgical resection of the tumor with adequate free margins.•The 5-year patient survival rate ranges from 59-to-100 %, whereas local recurrence is estimated to reach 8 % for benign SFTs.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>37058810</pmid><doi>10.1016/j.ijscr.2023.108168</doi><orcidid>https://orcid.org/0000-0002-0292-0287</orcidid><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 2210-2612 |
| ispartof | International journal of surgery case reports, 2023-05, Vol.106, p.108168, Article 108168 |
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| language | eng |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; ScienceDirect Journals (5 years ago - present); PubMed Central |
| subjects | Abdominal Surgery Case Report Pelvic Mass Solitary Fibrous Tumor Surgical Oncology |
| title | An extremely rare case of an isolated primary benign pelvic Solitary Fibrous Tumor in an elderly female |
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