Target search by an imported conjugative DNA element for a unique integration site along a bacterial chromosome during horizontal gene transfer

Abstract Integrative and conjugative elements (ICEs) are mobile genetic elements that can transfer by conjugation to recipient cells. Some ICEs integrate into a unique site in the genome of their hosts. We studied quantitatively the process by which an ICE searches for its unique integration site in...

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Veröffentlicht in:Nucleic acids research 2023-04, Vol.51 (7), p.3116-3129
Hauptverfasser: Arbel-Goren, Rinat, McKeithen-Mead, Saria A, Voglmaier, Dominik, Afremov, Idana, Teza, Gianluca, Grossman, Alan D, Stavans, Joel
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Sprache:eng
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