Pharmacokinetics of N,N-dimethyltryptamine in Humans

Background and Objective N , N -dimethyltryptamine (DMT) is a psychedelic compound under development for the treatment of major depressive disorder (MDD). This study evaluated the preclinical and clinical pharmacokinetics and metabolism of DMT in healthy subjects. Methods The physiochemical properti...

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Veröffentlicht in:	European journal of drug metabolism and pharmacokinetics 2023-05, Vol.48 (3), p.311-327
Hauptverfasser:	Good, Meghan, Joel, Zelah, Benway, Tiffanie, Routledge, Carol, Timmermann, Chris, Erritzoe, David, Weaver, Richard, Allen, Graham, Hughes, Charlotte, Topping, Helen, Bowman, Amy, James, Ellen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomedical and Life Sciences Biomedicine Cytochrome P-450 CYP2D6 - metabolism Depressive Disorder, Major - drug therapy Dose-Response Relationship, Drug Double-Blind Method Human Physiology Humans Kinetics Medical Biochemistry Monoamine Oxidase - metabolism N,N-Dimethyltryptamine NCT NCT04673383 Original Original Research Article Pharmaceutical Sciences/Technology Pharmacology/Toxicology Pharmacy
Online-Zugang:	Volltext
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