In Vitro Antibacterial and Phytochemical Screening of Hypericum perforatum Extract as Potential Antimicrobial Agents against Multi-Drug-Resistant (MDR) Strains of Clinical Origin

Background. The perennial plant Hypericum perforatum is widely distributed around the world. It has been used for many years in conventional medicine to treat a variety of illnesses, including stress, mild to moderate depression, and minor injuries. This study examined the antimicrobial activity of...

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Veröffentlicht in:	BioMed research international 2023, Vol.2023 (1), p.6934398
Hauptverfasser:	Sherif, Momen M., Elshikh, Hussien H., Abdel-Aziz, Marwa M., Elaasser, Mahmoud M., Yosri, Mohammed
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Acids Animals Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Antibacterial activity Antibiotics Antimicrobial activity Antimicrobial agents Antioxidants Antioxidants - chemistry Antioxidants - pharmacology Assaying Bacteria Biomedical research Chlorocebus aethiops Chloroform Chromatography Cytotoxicity Drug resistance Drug Resistance, Bacterial - drug effects Drug Resistance, Multiple - drug effects E coli Electron microscopy Enterococcus faecalis Enterococcus faecalis - drug effects Escherichia coli Escherichia coli - drug effects Ethyl acetate Gram-negative bacteria Gram-positive bacteria Hexanes Hypericum - chemistry Hypericum perforatum Klebsiella Klebsiella pneumoniae Klebsiella pneumoniae - drug effects Methicillin Methicillin-Resistant Staphylococcus aureus - drug effects Microbial Sensitivity Tests Minimum inhibitory concentration Multidrug resistance n-Hexane Phytochemicals Phytochemicals - chemistry Phytochemicals - pharmacology Plant Extracts - chemistry Plant Extracts - pharmacology Pneumonia Scavenging Staphylococcus aureus Staphylococcus infections Strains (organisms) Tandem Mass Spectrometry Toxicity Transmission electron microscopy Ultrastructure Vero Cells
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