Cell-Penetrating d‑Peptides Retain Antisense Morpholino Oligomer Delivery Activity

Cell-penetrating peptides (CPPs) can cross the cell membrane to enter the cytosol and deliver otherwise nonpenetrant macromolecules such as proteins and oligonucleotides. For example, recent clinical trials have shown that a CPP attached to phosphorodiamidate morpholino oligomers (PMOs) resulted in...

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Veröffentlicht in:	ACS bio & med chem au 2022-04, Vol.2 (2), p.150-160
Hauptverfasser:	Schissel, Carly K, Farquhar, Charlotte E, Malmberg, Annika B, Loas, Andrei, Pentelute, Bradley L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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