Symptom Assessment for Mechanically Ventilated Patients: Principles and Priorities: An Official American Thoracic Society Workshop Report
Mechanically ventilated patients experience many adverse symptoms, such as anxiety, thirst, and dyspnea. However, these common symptoms are not included in practice guideline recommendations for routine assessment of mechanically ventilated patients. An American Thoracic Society-sponsored workshop w...
Gespeichert in:
Veröffentlicht in: | Annals of the American Thoracic Society 2023-04, Vol.20 (4), p.491-498 |
---|---|
Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 498 |
---|---|
container_issue | 4 |
container_start_page | 491 |
container_title | Annals of the American Thoracic Society |
container_volume | 20 |
creator | Guttormson, Jill L Khan, Babar Brodsky, Martin B Chlan, Linda L Curley, Martha A Q Gélinas, Céline Happ, Mary Beth Herridge, Margaret Hess, Dean Hetland, Breanna Hopkins, Ramona O Hosey, Megan M Hosie, Annmarie Lodolo, Andrew C McAndrew, Natalie S Mehta, Sangeeta Misak, Cheryl Pisani, Margaret A van den Boogaard, Mark Wang, Sophia |
description | Mechanically ventilated patients experience many adverse symptoms, such as anxiety, thirst, and dyspnea. However, these common symptoms are not included in practice guideline recommendations for routine assessment of mechanically ventilated patients. An American Thoracic Society-sponsored workshop with researchers and clinicians with expertise in critical care and symptom management was convened for a discussion of symptom assessment in mechanically ventilated patients. Members included nurses, physicians, a respiratory therapist, a speech-language pathologist, a critical care pharmacist, and a former intensive care unit patient. This report summarizes existing evidence and consensus among workshop participants regarding
) symptoms that should be considered for routine assessment of adult patients receiving mechanical ventilation;
) key symptom assessment principles;
) strategies that support symptom assessment in nonvocal patients; and
) areas for future clinical practice development and research. Systematic patient-centered assessment of multiple symptoms has great potential to minimize patient distress and improve the patient experience. A culture shift is necessary to promote ongoing holistic symptom assessment with valid and reliable instruments. This report represents our workgroup consensus on symptom assessment for mechanically ventilated patients. Future work should address how holistic, patient-centered symptom assessment can be embedded into clinical practice. |
doi_str_mv | 10.1513/AnnalsATS.202301-023ST |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10112406</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2793990559</sourcerecordid><originalsourceid>FETCH-LOGICAL-c443t-1086e055fb14e46be29d99d6a1f79abbdb777a21f37b2c405e226275e03a7d033</originalsourceid><addsrcrecordid>eNpdUdtu1DAUtBCIVqW_UFnihZcU32LHvKCo4iYVtWIXeLQc54R1SexgZ5H2E_hrvN2yAvxgn_GZMzqjQeiCkktaU_6yDcGOuV2vLhlhnNCq3Kv1I3TKOKsrKRl9fF_rSmrOT9B5zneknKamjdJP0QlXBVEhTtGv1W6alzjhNmfIeYKw4CEm_BHcxgbv7Dju8Jfy60e7QI9v7eILyq_wbfLB-XmEjG3o9zAmX5ql1QZ8MwzeeTvidoJUZAJeb2Kyzju8is7DssNfY_qeN3HGn2COaXmGngzFFZw_vGfo89s366v31fXNuw9X7XXlhOBLRUkjgdT10FEBQnbAdK91Ly0dlLZd13dKKcvowFXHnCA1MCaZqoFwq3rC-Rl6fdCdt90EvStukh3NnPxk085E682_neA35lv8aSihlAkii8KLB4UUf2whL2by2cE42gBxmw1TmmtddtSF-vw_6l3cpn16e5ZopG5kXVjywHIp5pxgOG5Didknbo6Jm0Pi5j7xMnjxt5fj2J98-W-QeKvj</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2794869865</pqid></control><display><type>article</type><title>Symptom Assessment for Mechanically Ventilated Patients: Principles and Priorities: An Official American Thoracic Society Workshop Report</title><source>MEDLINE</source><source>American Thoracic Society (ATS) Journals Online</source><source>Alma/SFX Local Collection</source><creator>Guttormson, Jill L ; Khan, Babar ; Brodsky, Martin B ; Chlan, Linda L ; Curley, Martha A Q ; Gélinas, Céline ; Happ, Mary Beth ; Herridge, Margaret ; Hess, Dean ; Hetland, Breanna ; Hopkins, Ramona O ; Hosey, Megan M ; Hosie, Annmarie ; Lodolo, Andrew C ; McAndrew, Natalie S ; Mehta, Sangeeta ; Misak, Cheryl ; Pisani, Margaret A ; van den Boogaard, Mark ; Wang, Sophia</creator><creatorcontrib>Guttormson, Jill L ; Khan, Babar ; Brodsky, Martin B ; Chlan, Linda L ; Curley, Martha A Q ; Gélinas, Céline ; Happ, Mary Beth ; Herridge, Margaret ; Hess, Dean ; Hetland, Breanna ; Hopkins, Ramona O ; Hosey, Megan M ; Hosie, Annmarie ; Lodolo, Andrew C ; McAndrew, Natalie S ; Mehta, Sangeeta ; Misak, Cheryl ; Pisani, Margaret A ; van den Boogaard, Mark ; Wang, Sophia</creatorcontrib><description>Mechanically ventilated patients experience many adverse symptoms, such as anxiety, thirst, and dyspnea. However, these common symptoms are not included in practice guideline recommendations for routine assessment of mechanically ventilated patients. An American Thoracic Society-sponsored workshop with researchers and clinicians with expertise in critical care and symptom management was convened for a discussion of symptom assessment in mechanically ventilated patients. Members included nurses, physicians, a respiratory therapist, a speech-language pathologist, a critical care pharmacist, and a former intensive care unit patient. This report summarizes existing evidence and consensus among workshop participants regarding
) symptoms that should be considered for routine assessment of adult patients receiving mechanical ventilation;
) key symptom assessment principles;
) strategies that support symptom assessment in nonvocal patients; and
) areas for future clinical practice development and research. Systematic patient-centered assessment of multiple symptoms has great potential to minimize patient distress and improve the patient experience. A culture shift is necessary to promote ongoing holistic symptom assessment with valid and reliable instruments. This report represents our workgroup consensus on symptom assessment for mechanically ventilated patients. Future work should address how holistic, patient-centered symptom assessment can be embedded into clinical practice.</description><identifier>ISSN: 2329-6933</identifier><identifier>EISSN: 2325-6621</identifier><identifier>DOI: 10.1513/AnnalsATS.202301-023ST</identifier><identifier>PMID: 37000144</identifier><language>eng</language><publisher>United States: American Thoracic Society</publisher><subject>Adult ; American Thoracic Society Documents ; Anxiety - diagnosis ; Anxiety - etiology ; Critical Care ; Humans ; Intensive Care Units ; Patient assessment ; Respiration, Artificial - adverse effects ; Side effects ; Societies ; Symptom Assessment ; United States ; Ventilation</subject><ispartof>Annals of the American Thoracic Society, 2023-04, Vol.20 (4), p.491-498</ispartof><rights>Copyright American Thoracic Society Apr 2023</rights><rights>Copyright © 2023 by the American Thoracic Society 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c443t-1086e055fb14e46be29d99d6a1f79abbdb777a21f37b2c405e226275e03a7d033</citedby><cites>FETCH-LOGICAL-c443t-1086e055fb14e46be29d99d6a1f79abbdb777a21f37b2c405e226275e03a7d033</cites><orcidid>0000-0001-8601-7038 ; 0000-0003-4233-2903 ; 0000-0003-2980-4443 ; 0000-0001-5228-6694 ; 0000-0003-4373-4728 ; 0000-0003-2274-859X ; 0000-0003-4199-2643 ; 0000-0001-7269-1005 ; 0000-0002-3645-2944 ; 0000-0002-8572-6761 ; 0000-0003-1674-2124 ; 0000-0002-7073-4769</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37000144$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Guttormson, Jill L</creatorcontrib><creatorcontrib>Khan, Babar</creatorcontrib><creatorcontrib>Brodsky, Martin B</creatorcontrib><creatorcontrib>Chlan, Linda L</creatorcontrib><creatorcontrib>Curley, Martha A Q</creatorcontrib><creatorcontrib>Gélinas, Céline</creatorcontrib><creatorcontrib>Happ, Mary Beth</creatorcontrib><creatorcontrib>Herridge, Margaret</creatorcontrib><creatorcontrib>Hess, Dean</creatorcontrib><creatorcontrib>Hetland, Breanna</creatorcontrib><creatorcontrib>Hopkins, Ramona O</creatorcontrib><creatorcontrib>Hosey, Megan M</creatorcontrib><creatorcontrib>Hosie, Annmarie</creatorcontrib><creatorcontrib>Lodolo, Andrew C</creatorcontrib><creatorcontrib>McAndrew, Natalie S</creatorcontrib><creatorcontrib>Mehta, Sangeeta</creatorcontrib><creatorcontrib>Misak, Cheryl</creatorcontrib><creatorcontrib>Pisani, Margaret A</creatorcontrib><creatorcontrib>van den Boogaard, Mark</creatorcontrib><creatorcontrib>Wang, Sophia</creatorcontrib><title>Symptom Assessment for Mechanically Ventilated Patients: Principles and Priorities: An Official American Thoracic Society Workshop Report</title><title>Annals of the American Thoracic Society</title><addtitle>Ann Am Thorac Soc</addtitle><description>Mechanically ventilated patients experience many adverse symptoms, such as anxiety, thirst, and dyspnea. However, these common symptoms are not included in practice guideline recommendations for routine assessment of mechanically ventilated patients. An American Thoracic Society-sponsored workshop with researchers and clinicians with expertise in critical care and symptom management was convened for a discussion of symptom assessment in mechanically ventilated patients. Members included nurses, physicians, a respiratory therapist, a speech-language pathologist, a critical care pharmacist, and a former intensive care unit patient. This report summarizes existing evidence and consensus among workshop participants regarding
) symptoms that should be considered for routine assessment of adult patients receiving mechanical ventilation;
) key symptom assessment principles;
) strategies that support symptom assessment in nonvocal patients; and
) areas for future clinical practice development and research. Systematic patient-centered assessment of multiple symptoms has great potential to minimize patient distress and improve the patient experience. A culture shift is necessary to promote ongoing holistic symptom assessment with valid and reliable instruments. This report represents our workgroup consensus on symptom assessment for mechanically ventilated patients. Future work should address how holistic, patient-centered symptom assessment can be embedded into clinical practice.</description><subject>Adult</subject><subject>American Thoracic Society Documents</subject><subject>Anxiety - diagnosis</subject><subject>Anxiety - etiology</subject><subject>Critical Care</subject><subject>Humans</subject><subject>Intensive Care Units</subject><subject>Patient assessment</subject><subject>Respiration, Artificial - adverse effects</subject><subject>Side effects</subject><subject>Societies</subject><subject>Symptom Assessment</subject><subject>United States</subject><subject>Ventilation</subject><issn>2329-6933</issn><issn>2325-6621</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUdtu1DAUtBCIVqW_UFnihZcU32LHvKCo4iYVtWIXeLQc54R1SexgZ5H2E_hrvN2yAvxgn_GZMzqjQeiCkktaU_6yDcGOuV2vLhlhnNCq3Kv1I3TKOKsrKRl9fF_rSmrOT9B5zneknKamjdJP0QlXBVEhTtGv1W6alzjhNmfIeYKw4CEm_BHcxgbv7Dju8Jfy60e7QI9v7eILyq_wbfLB-XmEjG3o9zAmX5ql1QZ8MwzeeTvidoJUZAJeb2Kyzju8is7DssNfY_qeN3HGn2COaXmGngzFFZw_vGfo89s366v31fXNuw9X7XXlhOBLRUkjgdT10FEBQnbAdK91Ly0dlLZd13dKKcvowFXHnCA1MCaZqoFwq3rC-Rl6fdCdt90EvStukh3NnPxk085E682_neA35lv8aSihlAkii8KLB4UUf2whL2by2cE42gBxmw1TmmtddtSF-vw_6l3cpn16e5ZopG5kXVjywHIp5pxgOG5Didknbo6Jm0Pi5j7xMnjxt5fj2J98-W-QeKvj</recordid><startdate>202304</startdate><enddate>202304</enddate><creator>Guttormson, Jill L</creator><creator>Khan, Babar</creator><creator>Brodsky, Martin B</creator><creator>Chlan, Linda L</creator><creator>Curley, Martha A Q</creator><creator>Gélinas, Céline</creator><creator>Happ, Mary Beth</creator><creator>Herridge, Margaret</creator><creator>Hess, Dean</creator><creator>Hetland, Breanna</creator><creator>Hopkins, Ramona O</creator><creator>Hosey, Megan M</creator><creator>Hosie, Annmarie</creator><creator>Lodolo, Andrew C</creator><creator>McAndrew, Natalie S</creator><creator>Mehta, Sangeeta</creator><creator>Misak, Cheryl</creator><creator>Pisani, Margaret A</creator><creator>van den Boogaard, Mark</creator><creator>Wang, Sophia</creator><general>American Thoracic Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8601-7038</orcidid><orcidid>https://orcid.org/0000-0003-4233-2903</orcidid><orcidid>https://orcid.org/0000-0003-2980-4443</orcidid><orcidid>https://orcid.org/0000-0001-5228-6694</orcidid><orcidid>https://orcid.org/0000-0003-4373-4728</orcidid><orcidid>https://orcid.org/0000-0003-2274-859X</orcidid><orcidid>https://orcid.org/0000-0003-4199-2643</orcidid><orcidid>https://orcid.org/0000-0001-7269-1005</orcidid><orcidid>https://orcid.org/0000-0002-3645-2944</orcidid><orcidid>https://orcid.org/0000-0002-8572-6761</orcidid><orcidid>https://orcid.org/0000-0003-1674-2124</orcidid><orcidid>https://orcid.org/0000-0002-7073-4769</orcidid></search><sort><creationdate>202304</creationdate><title>Symptom Assessment for Mechanically Ventilated Patients: Principles and Priorities: An Official American Thoracic Society Workshop Report</title><author>Guttormson, Jill L ; Khan, Babar ; Brodsky, Martin B ; Chlan, Linda L ; Curley, Martha A Q ; Gélinas, Céline ; Happ, Mary Beth ; Herridge, Margaret ; Hess, Dean ; Hetland, Breanna ; Hopkins, Ramona O ; Hosey, Megan M ; Hosie, Annmarie ; Lodolo, Andrew C ; McAndrew, Natalie S ; Mehta, Sangeeta ; Misak, Cheryl ; Pisani, Margaret A ; van den Boogaard, Mark ; Wang, Sophia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c443t-1086e055fb14e46be29d99d6a1f79abbdb777a21f37b2c405e226275e03a7d033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Adult</topic><topic>American Thoracic Society Documents</topic><topic>Anxiety - diagnosis</topic><topic>Anxiety - etiology</topic><topic>Critical Care</topic><topic>Humans</topic><topic>Intensive Care Units</topic><topic>Patient assessment</topic><topic>Respiration, Artificial - adverse effects</topic><topic>Side effects</topic><topic>Societies</topic><topic>Symptom Assessment</topic><topic>United States</topic><topic>Ventilation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Guttormson, Jill L</creatorcontrib><creatorcontrib>Khan, Babar</creatorcontrib><creatorcontrib>Brodsky, Martin B</creatorcontrib><creatorcontrib>Chlan, Linda L</creatorcontrib><creatorcontrib>Curley, Martha A Q</creatorcontrib><creatorcontrib>Gélinas, Céline</creatorcontrib><creatorcontrib>Happ, Mary Beth</creatorcontrib><creatorcontrib>Herridge, Margaret</creatorcontrib><creatorcontrib>Hess, Dean</creatorcontrib><creatorcontrib>Hetland, Breanna</creatorcontrib><creatorcontrib>Hopkins, Ramona O</creatorcontrib><creatorcontrib>Hosey, Megan M</creatorcontrib><creatorcontrib>Hosie, Annmarie</creatorcontrib><creatorcontrib>Lodolo, Andrew C</creatorcontrib><creatorcontrib>McAndrew, Natalie S</creatorcontrib><creatorcontrib>Mehta, Sangeeta</creatorcontrib><creatorcontrib>Misak, Cheryl</creatorcontrib><creatorcontrib>Pisani, Margaret A</creatorcontrib><creatorcontrib>van den Boogaard, Mark</creatorcontrib><creatorcontrib>Wang, Sophia</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of the American Thoracic Society</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Guttormson, Jill L</au><au>Khan, Babar</au><au>Brodsky, Martin B</au><au>Chlan, Linda L</au><au>Curley, Martha A Q</au><au>Gélinas, Céline</au><au>Happ, Mary Beth</au><au>Herridge, Margaret</au><au>Hess, Dean</au><au>Hetland, Breanna</au><au>Hopkins, Ramona O</au><au>Hosey, Megan M</au><au>Hosie, Annmarie</au><au>Lodolo, Andrew C</au><au>McAndrew, Natalie S</au><au>Mehta, Sangeeta</au><au>Misak, Cheryl</au><au>Pisani, Margaret A</au><au>van den Boogaard, Mark</au><au>Wang, Sophia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Symptom Assessment for Mechanically Ventilated Patients: Principles and Priorities: An Official American Thoracic Society Workshop Report</atitle><jtitle>Annals of the American Thoracic Society</jtitle><addtitle>Ann Am Thorac Soc</addtitle><date>2023-04</date><risdate>2023</risdate><volume>20</volume><issue>4</issue><spage>491</spage><epage>498</epage><pages>491-498</pages><issn>2329-6933</issn><eissn>2325-6621</eissn><abstract>Mechanically ventilated patients experience many adverse symptoms, such as anxiety, thirst, and dyspnea. However, these common symptoms are not included in practice guideline recommendations for routine assessment of mechanically ventilated patients. An American Thoracic Society-sponsored workshop with researchers and clinicians with expertise in critical care and symptom management was convened for a discussion of symptom assessment in mechanically ventilated patients. Members included nurses, physicians, a respiratory therapist, a speech-language pathologist, a critical care pharmacist, and a former intensive care unit patient. This report summarizes existing evidence and consensus among workshop participants regarding
) symptoms that should be considered for routine assessment of adult patients receiving mechanical ventilation;
) key symptom assessment principles;
) strategies that support symptom assessment in nonvocal patients; and
) areas for future clinical practice development and research. Systematic patient-centered assessment of multiple symptoms has great potential to minimize patient distress and improve the patient experience. A culture shift is necessary to promote ongoing holistic symptom assessment with valid and reliable instruments. This report represents our workgroup consensus on symptom assessment for mechanically ventilated patients. Future work should address how holistic, patient-centered symptom assessment can be embedded into clinical practice.</abstract><cop>United States</cop><pub>American Thoracic Society</pub><pmid>37000144</pmid><doi>10.1513/AnnalsATS.202301-023ST</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-8601-7038</orcidid><orcidid>https://orcid.org/0000-0003-4233-2903</orcidid><orcidid>https://orcid.org/0000-0003-2980-4443</orcidid><orcidid>https://orcid.org/0000-0001-5228-6694</orcidid><orcidid>https://orcid.org/0000-0003-4373-4728</orcidid><orcidid>https://orcid.org/0000-0003-2274-859X</orcidid><orcidid>https://orcid.org/0000-0003-4199-2643</orcidid><orcidid>https://orcid.org/0000-0001-7269-1005</orcidid><orcidid>https://orcid.org/0000-0002-3645-2944</orcidid><orcidid>https://orcid.org/0000-0002-8572-6761</orcidid><orcidid>https://orcid.org/0000-0003-1674-2124</orcidid><orcidid>https://orcid.org/0000-0002-7073-4769</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 2329-6933 |
ispartof | Annals of the American Thoracic Society, 2023-04, Vol.20 (4), p.491-498 |
issn | 2329-6933 2325-6621 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10112406 |
source | MEDLINE; American Thoracic Society (ATS) Journals Online; Alma/SFX Local Collection |
subjects | Adult American Thoracic Society Documents Anxiety - diagnosis Anxiety - etiology Critical Care Humans Intensive Care Units Patient assessment Respiration, Artificial - adverse effects Side effects Societies Symptom Assessment United States Ventilation |
title | Symptom Assessment for Mechanically Ventilated Patients: Principles and Priorities: An Official American Thoracic Society Workshop Report |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T17%3A04%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Symptom%20Assessment%20for%20Mechanically%20Ventilated%20Patients:%20Principles%20and%20Priorities:%20An%20Official%20American%20Thoracic%20Society%20Workshop%20Report&rft.jtitle=Annals%20of%20the%20American%20Thoracic%20Society&rft.au=Guttormson,%20Jill%20L&rft.date=2023-04&rft.volume=20&rft.issue=4&rft.spage=491&rft.epage=498&rft.pages=491-498&rft.issn=2329-6933&rft.eissn=2325-6621&rft_id=info:doi/10.1513/AnnalsATS.202301-023ST&rft_dat=%3Cproquest_pubme%3E2793990559%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2794869865&rft_id=info:pmid/37000144&rfr_iscdi=true |