HIF1α-dependent and independent pathways regulate the expression of PD-L1 in prostate cancer

PD-L1/PD-1 pathway is a major pathway exploited by human cancer types, which is a target for current immunotherapy. We investigated tumor microenvironmental factors involved in PD-L1 induction in prostate cancer (PC). We studied the expression of PD-L1 in a series of 66 PCs, in parallel with the exp...

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Veröffentlicht in:	Medical oncology (Northwood, London, England) London, England), 2023-04, Vol.40 (5), p.151-151, Article 151
Hauptverfasser:	Xanthopoulou, Erasmia T., Kakouratos, Christos, Nanos, Christos, Gkegka, Anastasia G., Kalaitzis, Christos, Giatromanolaki, Alexandra, Koukourakis, Michael I.
Format:	Artikel
Sprache:	eng
Schlagworte:	B7-H1 Antigen - genetics B7-H1 Antigen - metabolism Cell Line, Tumor Hematology Humans Hypoxia Hypoxia - pathology Immunotherapy Internal Medicine Lymphocytes, Tumor-Infiltrating - pathology Male Medicine Medicine & Public Health Oncology Original Paper Pathology Programmed Cell Death 1 Receptor - metabolism Prostate cancer Prostatic Neoplasms - pathology RNA, Messenger
Online-Zugang:	Volltext
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