Prolactin-Secreting Pituitary Adenomas
Prolactin-secreting pituitary adenoma is a common cause of gynecologic problems that include oligomenorrhea, infertility, amenorrhea and galactorrhea. Diagnosis requires a combination of endocrine testing and radiologic evaluation. The diagnosis of macroadenomas is usually straightforward and these...
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Veröffentlicht in: | The Western journal of medicine 1983-11, Vol.139 (5), p.663-672 |
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description | Prolactin-secreting pituitary adenoma is a common cause of gynecologic problems that include oligomenorrhea, infertility, amenorrhea and galactorrhea. Diagnosis requires a combination of endocrine testing and radiologic evaluation. The diagnosis of macroadenomas is usually straightforward and these large tumors may be associated with mass effects such as severe headache, nerve palsies or visual changes. Microadenomas may be more subtle in presentation, and the diagnosis of hyperprolactinemia without radiologic evidence of a tumor frequently is problematic. The management of prolactin-secreting adenoma remains controversial, with no clear consensus or indication for surgical versus medical treatment. Surgical intervention is a realistic option for those patients who have access to an experienced neurosurgeon and who have tumor characteristics that offer a reasonable hope for cure. Many questions remain to be answered, including the cause, natural history of development and the optimum treatment for individual cases. Images |
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Diagnosis requires a combination of endocrine testing and radiologic evaluation. The diagnosis of macroadenomas is usually straightforward and these large tumors may be associated with mass effects such as severe headache, nerve palsies or visual changes. Microadenomas may be more subtle in presentation, and the diagnosis of hyperprolactinemia without radiologic evidence of a tumor frequently is problematic. The management of prolactin-secreting adenoma remains controversial, with no clear consensus or indication for surgical versus medical treatment. Surgical intervention is a realistic option for those patients who have access to an experienced neurosurgeon and who have tumor characteristics that offer a reasonable hope for cure. Many questions remain to be answered, including the cause, natural history of development and the optimum treatment for individual cases. Images</description><identifier>ISSN: 0093-0415</identifier><identifier>EISSN: 1476-2978</identifier><identifier>PMID: 6659490</identifier><identifier>CODEN: WJMDA2</identifier><language>eng</language><publisher>United States: BMJ Publishing Group LTD</publisher><subject>Adenoma - diagnostic imaging ; Adenoma - secretion ; Adenoma - therapy ; Bromocriptine - therapeutic use ; Female ; Humans ; Medical Progress ; Pituitary Neoplasms - diagnostic imaging ; Pituitary Neoplasms - secretion ; Pituitary Neoplasms - therapy ; Pregnancy ; Pregnancy Complications, Neoplastic - therapy ; Prolactin - analysis ; Prolactin - secretion ; Radioimmunoassay ; Tomography, X-Ray Computed</subject><ispartof>The Western journal of medicine, 1983-11, Vol.139 (5), p.663-672</ispartof><rights>Copyright BMJ Publishing Group LTD Nov 1983</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1010965/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1010965/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,724,777,781,882,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6659490$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Martin, Mary C.</creatorcontrib><creatorcontrib>Schriock, Eldon D.</creatorcontrib><creatorcontrib>Jaffe, Robert B.</creatorcontrib><title>Prolactin-Secreting Pituitary Adenomas</title><title>The Western journal of medicine</title><addtitle>West J Med</addtitle><description>Prolactin-secreting pituitary adenoma is a common cause of gynecologic problems that include oligomenorrhea, infertility, amenorrhea and galactorrhea. Diagnosis requires a combination of endocrine testing and radiologic evaluation. The diagnosis of macroadenomas is usually straightforward and these large tumors may be associated with mass effects such as severe headache, nerve palsies or visual changes. Microadenomas may be more subtle in presentation, and the diagnosis of hyperprolactinemia without radiologic evidence of a tumor frequently is problematic. The management of prolactin-secreting adenoma remains controversial, with no clear consensus or indication for surgical versus medical treatment. Surgical intervention is a realistic option for those patients who have access to an experienced neurosurgeon and who have tumor characteristics that offer a reasonable hope for cure. Many questions remain to be answered, including the cause, natural history of development and the optimum treatment for individual cases. Images</description><subject>Adenoma - diagnostic imaging</subject><subject>Adenoma - secretion</subject><subject>Adenoma - therapy</subject><subject>Bromocriptine - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Medical Progress</subject><subject>Pituitary Neoplasms - diagnostic imaging</subject><subject>Pituitary Neoplasms - secretion</subject><subject>Pituitary Neoplasms - therapy</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Neoplastic - therapy</subject><subject>Prolactin - analysis</subject><subject>Prolactin - secretion</subject><subject>Radioimmunoassay</subject><subject>Tomography, X-Ray Computed</subject><issn>0093-0415</issn><issn>1476-2978</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkNtKAzEQhoMotVYfQSgIvVuYbE6bG6HUQ5WiVat4F7LZbE3dQ012Rd_ehZaiXs3A9_PzzeyhPqaCR7EUyT7qA0gSAcXsEB2FsAIAyrDsoR7nTFIJfTSa-7rQpnFV9GSNt92yHM5d07pG--_hOLNVXepwjA5yXQR7sp0D9Hx1uZhMo9n99c1kPIsciUUTZRnRKQcbZ2kKQuZWMJnJ3HDNck0hp5jK2EpqOGUGm8xICwKoTDBNaQycDND5pnfdpqXNjK0arwu19q7sdFStnfpLKvemlvWnwoBBctYVjLYFvv5obWhU6YKxRaErW7dBJZAQQijugmf_gqu69VV3nMJCUIljCXGXOv3tsxPZ_q_j0Ya70NivHdb-XXFBBFN3LxOFHxa3j4uLVzUlP6-fe_4</recordid><startdate>19831101</startdate><enddate>19831101</enddate><creator>Martin, Mary C.</creator><creator>Schriock, Eldon D.</creator><creator>Jaffe, Robert B.</creator><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19831101</creationdate><title>Prolactin-Secreting Pituitary Adenomas</title><author>Martin, Mary C. ; Schriock, Eldon D. ; Jaffe, Robert B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i327t-dd3ab60e2dbb079fe759d9fc6a5fa40f41492e94c645c1cdc9e07049814b42063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Adenoma - diagnostic imaging</topic><topic>Adenoma - secretion</topic><topic>Adenoma - therapy</topic><topic>Bromocriptine - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Medical Progress</topic><topic>Pituitary Neoplasms - diagnostic imaging</topic><topic>Pituitary Neoplasms - secretion</topic><topic>Pituitary Neoplasms - therapy</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Neoplastic - therapy</topic><topic>Prolactin - analysis</topic><topic>Prolactin - secretion</topic><topic>Radioimmunoassay</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Martin, Mary C.</creatorcontrib><creatorcontrib>Schriock, Eldon D.</creatorcontrib><creatorcontrib>Jaffe, Robert B.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Western journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Martin, Mary C.</au><au>Schriock, Eldon D.</au><au>Jaffe, Robert B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prolactin-Secreting Pituitary Adenomas</atitle><jtitle>The Western journal of medicine</jtitle><addtitle>West J Med</addtitle><date>1983-11-01</date><risdate>1983</risdate><volume>139</volume><issue>5</issue><spage>663</spage><epage>672</epage><pages>663-672</pages><issn>0093-0415</issn><eissn>1476-2978</eissn><coden>WJMDA2</coden><abstract>Prolactin-secreting pituitary adenoma is a common cause of gynecologic problems that include oligomenorrhea, infertility, amenorrhea and galactorrhea. Diagnosis requires a combination of endocrine testing and radiologic evaluation. The diagnosis of macroadenomas is usually straightforward and these large tumors may be associated with mass effects such as severe headache, nerve palsies or visual changes. Microadenomas may be more subtle in presentation, and the diagnosis of hyperprolactinemia without radiologic evidence of a tumor frequently is problematic. The management of prolactin-secreting adenoma remains controversial, with no clear consensus or indication for surgical versus medical treatment. Surgical intervention is a realistic option for those patients who have access to an experienced neurosurgeon and who have tumor characteristics that offer a reasonable hope for cure. Many questions remain to be answered, including the cause, natural history of development and the optimum treatment for individual cases. Images</abstract><cop>United States</cop><pub>BMJ Publishing Group LTD</pub><pmid>6659490</pmid><tpages>10</tpages></addata></record> |
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subjects | Adenoma - diagnostic imaging Adenoma - secretion Adenoma - therapy Bromocriptine - therapeutic use Female Humans Medical Progress Pituitary Neoplasms - diagnostic imaging Pituitary Neoplasms - secretion Pituitary Neoplasms - therapy Pregnancy Pregnancy Complications, Neoplastic - therapy Prolactin - analysis Prolactin - secretion Radioimmunoassay Tomography, X-Ray Computed |
title | Prolactin-Secreting Pituitary Adenomas |
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