Prolactin-Secreting Pituitary Adenomas

Prolactin-secreting pituitary adenoma is a common cause of gynecologic problems that include oligomenorrhea, infertility, amenorrhea and galactorrhea. Diagnosis requires a combination of endocrine testing and radiologic evaluation. The diagnosis of macroadenomas is usually straightforward and these...

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Veröffentlicht in:The Western journal of medicine 1983-11, Vol.139 (5), p.663-672
Hauptverfasser: Martin, Mary C., Schriock, Eldon D., Jaffe, Robert B.
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container_title The Western journal of medicine
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creator Martin, Mary C.
Schriock, Eldon D.
Jaffe, Robert B.
description Prolactin-secreting pituitary adenoma is a common cause of gynecologic problems that include oligomenorrhea, infertility, amenorrhea and galactorrhea. Diagnosis requires a combination of endocrine testing and radiologic evaluation. The diagnosis of macroadenomas is usually straightforward and these large tumors may be associated with mass effects such as severe headache, nerve palsies or visual changes. Microadenomas may be more subtle in presentation, and the diagnosis of hyperprolactinemia without radiologic evidence of a tumor frequently is problematic. The management of prolactin-secreting adenoma remains controversial, with no clear consensus or indication for surgical versus medical treatment. Surgical intervention is a realistic option for those patients who have access to an experienced neurosurgeon and who have tumor characteristics that offer a reasonable hope for cure. Many questions remain to be answered, including the cause, natural history of development and the optimum treatment for individual cases. Images
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subjects Adenoma - diagnostic imaging
Adenoma - secretion
Adenoma - therapy
Bromocriptine - therapeutic use
Female
Humans
Medical Progress
Pituitary Neoplasms - diagnostic imaging
Pituitary Neoplasms - secretion
Pituitary Neoplasms - therapy
Pregnancy
Pregnancy Complications, Neoplastic - therapy
Prolactin - analysis
Prolactin - secretion
Radioimmunoassay
Tomography, X-Ray Computed
title Prolactin-Secreting Pituitary Adenomas
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