The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries

Specific microbial signals induce the differentiation of a distinct pool of RORγ+ regulatory T (Treg) cells crucial for intestinal homeostasis. We discovered highly analogous populations of microbiota-dependent Treg cells that promoted tissue regeneration at extra-gut sites, notably acutely injured...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2023-04, Vol.56 (4), p.829-846.e8
Hauptverfasser:	Hanna, Bola S., Wang, Gang, Galván-Peña, Silvia, Mann, Alexander O., Ramirez, Ricardo N., Muñoz-Rojas, Andrés R., Smith, Kathleen, Wan, Min, Benoist, Christophe, Mathis, Diane
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals colon Gastrointestinal Microbiome IL-17 liver Mice Mice, Inbred C57BL Microbiota muscle NASH Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics RORγ stem cell T-Lymphocytes, Regulatory tissue regeneration Treg
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