Global Metabolomic Profiling of Host Red Blood Cells Infected with Babesia divergens Reveals Novel Antiparasitic Target Pathways

Babesia divergens is an apicomplexan parasite that infects human red blood cells (RBCs), initiating cycles of invasion, replication, and egress, resulting in extensive metabolic modification of the host cells. Babesia is an auxotroph for most of the nutrients required to sustain these cycles. There...

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Veröffentlicht in:Microbiology spectrum 2023-02, Vol.11 (2), p.e0468822-e0468822
Hauptverfasser: Beri, Divya, Singh, Manpreet, Rodriguez, Marilis, Goyal, Naman, Rasquinha, Giselle, Liu, Yunfeng, An, Xiuli, Yazdanbakhsh, Karina, Lobo, Cheryl A
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Sprache:eng
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