Synthetic Studies with Bacitracin A and Preparation of Analogues Containing Alternative Zinc Binding Groups

The growing threat of drug‐resistant bacteria is a global concern, highlighting the urgent need for new antibiotics and antibacterial strategies. In this light, practical synthetic access to natural product antibiotics can provide important structure‐activity insights while also opening avenues for...

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Veröffentlicht in:	Chembiochem : a European journal of chemical biology 2022-12, Vol.23 (24), p.e202200547-n/a
Hauptverfasser:	Buijs, Ned, Vlaming, Halana C., Haren, Matthijs J., Martin, Nathaniel I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial activity antibiotic resistance Antibiotics Bacitracin Bacitracin - chemistry Bacitracin - pharmacology Binding Natural products peptide synthesis Thiazoline Zinc
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