Fabrication and Assessment of Orodispersible Tablets Loaded with Cubosomes for the Improved Anticancer Activity of Simvastatin against the MDA-MB-231 Breast Cancer Cell Line

Various factors limit the use of simvastatin as an anticancer drug. Therefore, this study aimed to analyse simvastatin (SIM)-loaded cubosome efficacy against breast cancer. SIM-loaded cubosomes were prepared using the emulsification method using different glyceryl monooleate, Pluronic F127 (PF-127),...

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Veröffentlicht in:	Polymers 2023-04, Vol.15 (7), p.1774
Hauptverfasser:	Zaki, Randa Mohammed, El Sayeh Abou El Ela, Amal, Almurshedi, Alanood S, Aldosari, Basmah Nasser, Aldossari, Abdullah A, Ibrahim, Mohamed A
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antilipemic agents Biodegradable materials Breast cancer Cancer Cardiovascular disease Care and treatment Cholesterol Disintegration Dissolution Drug delivery systems Drugs Efficiency Entrapment Formulations Lipids Lymphatic system Metabolism Pharmaceutical industry Poloxamers Polyvinyl alcohol Simvastatin Spectrum analysis Statins Tablets Toxicity
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