Cannabidiol as a Modulator of the Development of Alcohol Tolerance in Rats

The study aimed to explore in vivo the influence of cannabidiol (CBD) on the development of alcohol tolerance in rats. Rats were treated with ethanol (3.0 g/kg, i.p.) and CBD (20 mg/kg, p.o.) for nine successive days, and rectal body temperature, sedation (sleeping time), and blood alcohol concentra...

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Veröffentlicht in:	Nutrients 2023-03, Vol.15 (7), p.1702
Hauptverfasser:	Szulc, Michał, Kujawski, Radosław, Pacholak, Amanda, Poprawska, Marta, Czora-Poczwardowska, Kamila, Geppert, Bogna, Mikołajczak, Przemysław Ł
Format:	Artikel
Sprache:	eng
Schlagworte:	Abstinence Addictions Alcohol use Alcoholism Alcohols Animals Blood Alcohol Content Blood levels Body temperature Cannabidiol Cannabidiol - pharmacology Cannabinoids Development and progression Dopamine D1 receptors Dopamine D2 receptors Dopamine D4 receptors Dopamine D5 receptors Dopamine receptors Drug addiction Drug dependence Drug tolerance Drug withdrawal Ethanol Ethanol - pharmacology Hippocampus In vivo methods and tests Ligands Marijuana Neostriatum Nervous system Pets Physiology Prefrontal Cortex Prevention Rats Rodents
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