Long Non-Coding RNAs (lncRNAs) as Regulators of the PI3K/AKT/mTOR Pathway in Gastric Carcinoma

Gastric cancer (GC) represents ~10% of the global cancer-related deaths, increasingly affecting the younger population in active stages of life. The high mortality of GC is due to late diagnosis, the presence of metastasis and drug resistance development. Additionally, current clinical markers do no...

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Veröffentlicht in:	International journal of molecular sciences 2023-03, Vol.24 (7), p.6294
Hauptverfasser:	Riquelme, Ismael, Pérez-Moreno, Pablo, Mora-Lagos, Bárbara, Ili, Carmen, Brebi, Priscilla, Roa, Juan Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Biomarkers Cancer Carcinoma Cell growth Chile Drug resistance Gastric cancer Gene expression Health aspects Humans Kinases Malignancy Metastases Metastasis MicroRNAs Molecular modelling Mortality Non-coding RNA Phosphatidylinositol 3-Kinases - metabolism Proto-Oncogene Proteins c-akt - metabolism Review RNA RNA, Long Noncoding - metabolism Signal transduction Stomach cancer Stomach Neoplasms - pathology Therapeutic applications Therapeutic targets TOR protein TOR Serine-Threonine Kinases - genetics TOR Serine-Threonine Kinases - metabolism Tumors
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