Contribution of the L-Type Amino Acid Transporter Family in the Diagnosis and Treatment of Prostate Cancer

The L-type amino acid transporter (LAT) family contains four members, LAT1~4, which are important amino acid transporters. They mainly transport specific amino acids through cell membranes, provide nutrients to cells, and are involved in a variety of metabolic pathways. They regulate the mTOR signal...

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Veröffentlicht in:	International journal of molecular sciences 2023-03, Vol.24 (7), p.6178
Hauptverfasser:	Zhao, Xue, Sakamoto, Shinichi, Wei, Jiaxing, Pae, Sangjon, Saito, Shinpei, Sazuka, Tomokazu, Imamura, Yusuke, Anzai, Naohiko, Ichikawa, Tomohiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Transport Systems - genetics Amino Acid Transport Systems - metabolism Amino acids Amino Acids - metabolism Angiogenesis Blood-brain barrier Cancer Care and treatment Castration Cell growth Cell membranes Cell proliferation Chemoresistance Chemotherapy Development and progression Diagnosis Drug delivery Drug development Embryos Humans Lymphocytes Male Medical diagnosis Medical prognosis Metabolic pathways Metabolism Nutrients Physiology Prostate cancer Prostatic Neoplasms - diagnosis Prostatic Neoplasms - genetics Prostatic Neoplasms - therapy Proteins Rapamycin Review Signal Transduction T cell receptors Therapeutic targets TOR protein TOR Serine-Threonine Kinases - genetics TOR Serine-Threonine Kinases - metabolism Tumor cells Tumors
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