A Comparison of Etiology, Pathogenesis, Vaccinal and Antiviral Drug Development between Influenza and COVID-19
Influenza virus and coronavirus, two kinds of pathogens that exist widely in nature, are common emerging pathogens that cause respiratory tract infections in humans. In December 2019, a novel coronavirus SARS-CoV-2 emerged, causing a severe respiratory infection named COVID-19 in humans, and raising...
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Veröffentlicht in: | International journal of molecular sciences 2023-03, Vol.24 (7), p.6369 |
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description | Influenza virus and coronavirus, two kinds of pathogens that exist widely in nature, are common emerging pathogens that cause respiratory tract infections in humans. In December 2019, a novel coronavirus SARS-CoV-2 emerged, causing a severe respiratory infection named COVID-19 in humans, and raising a global pandemic which has persisted in the world for almost three years. Influenza virus, a seasonally circulating respiratory pathogen, has caused four global pandemics in humans since 1918 by the emergence of novel variants. Studies have shown that there are certain similarities in transmission mode and pathogenesis between influenza and COVID-19, and vaccination and antiviral drugs are considered to have positive roles as well as several limitations in the prevention and control of both diseases. Comparative understandings would be helpful to the prevention and control of these diseases. Here, we review the study progress in the etiology, pathogenesis, vaccine and antiviral drug development for the two diseases. |
doi_str_mv | 10.3390/ijms24076369 |
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In December 2019, a novel coronavirus SARS-CoV-2 emerged, causing a severe respiratory infection named COVID-19 in humans, and raising a global pandemic which has persisted in the world for almost three years. Influenza virus, a seasonally circulating respiratory pathogen, has caused four global pandemics in humans since 1918 by the emergence of novel variants. Studies have shown that there are certain similarities in transmission mode and pathogenesis between influenza and COVID-19, and vaccination and antiviral drugs are considered to have positive roles as well as several limitations in the prevention and control of both diseases. Comparative understandings would be helpful to the prevention and control of these diseases. Here, we review the study progress in the etiology, pathogenesis, vaccine and antiviral drug development for the two diseases.</description><identifier>ISSN: 1422-0067</identifier><identifier>ISSN: 1661-6596</identifier><identifier>EISSN: 1422-0067</identifier><identifier>DOI: 10.3390/ijms24076369</identifier><identifier>PMID: 37047339</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Antiviral agents ; Antiviral Agents - pharmacology ; Antiviral Agents - therapeutic use ; Antiviral drugs ; Causes and theories of causation ; China ; Comparative analysis ; Coronaviruses ; COVID-19 ; Development and progression ; Diseases ; Drug Development ; Epidemics ; Etiology ; Health aspects ; Humans ; Influenza ; Influenza Vaccines ; Influenza, Human - drug therapy ; Influenza, Human - prevention & control ; Lung diseases ; Mutation ; Pandemics ; Pathogenesis ; Pathogens ; Respiratory tract diseases ; Respiratory Tract Infections - drug therapy ; Review ; SARS-CoV-2 ; Severe acute respiratory syndrome coronavirus 2 ; United Kingdom ; Vaccination ; Viruses</subject><ispartof>International journal of molecular sciences, 2023-03, Vol.24 (7), p.6369</ispartof><rights>COPYRIGHT 2023 MDPI AG</rights><rights>2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). 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In December 2019, a novel coronavirus SARS-CoV-2 emerged, causing a severe respiratory infection named COVID-19 in humans, and raising a global pandemic which has persisted in the world for almost three years. Influenza virus, a seasonally circulating respiratory pathogen, has caused four global pandemics in humans since 1918 by the emergence of novel variants. Studies have shown that there are certain similarities in transmission mode and pathogenesis between influenza and COVID-19, and vaccination and antiviral drugs are considered to have positive roles as well as several limitations in the prevention and control of both diseases. Comparative understandings would be helpful to the prevention and control of these diseases. 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subjects | Antiviral agents Antiviral Agents - pharmacology Antiviral Agents - therapeutic use Antiviral drugs Causes and theories of causation China Comparative analysis Coronaviruses COVID-19 Development and progression Diseases Drug Development Epidemics Etiology Health aspects Humans Influenza Influenza Vaccines Influenza, Human - drug therapy Influenza, Human - prevention & control Lung diseases Mutation Pandemics Pathogenesis Pathogens Respiratory tract diseases Respiratory Tract Infections - drug therapy Review SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 United Kingdom Vaccination Viruses |
title | A Comparison of Etiology, Pathogenesis, Vaccinal and Antiviral Drug Development between Influenza and COVID-19 |
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