CSF2RB overexpression promotes the protective effects of mesenchymal stromal cells against ischemic heart injury

The invasive intramyocardial injection of mesenchymal stromal cells (MSCs) allows for limited repeat injections and shows poor therapeutic efficacy against ischemic heart failure. Intravenous injection is an alternative method because this route allows for repeated, noninvasive, and easy delivery. H...

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Veröffentlicht in:	Theranostics 2023-01, Vol.13 (6), p.1759-1773
Hauptverfasser:	Qi, Tingting, Xu, Xiaoming, Guo, Yongzhen, Xia, Yunlong, Peng, Lu, Li, Congye, Ding, Fengyue, Gao, Chao, Fan, Miaomiao, Yu, Min, Zhao, Huishou, He, Yuan, Li, Wenli, Hai, Chunxu, Gao, Erhe, Zhang, Xing, Gao, Feng, Fan, Yanhong, Yan, Wenjun, Tao, Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses Animals Apoptosis Body fat Cardiac function Cardiovascular disease Chemokines Coronary vessels Cytokine Receptor Common beta Subunit - metabolism Growth factors Heart Heart Failure - therapy Hemodynamics Infections Laboratory animals Mesenchymal Stem Cell Transplantation - methods Mesenchymal Stem Cells - metabolism Mice Myocardial Ischemia - therapy Research Paper STAT5 Transcription Factor - metabolism Stem cells Stroke Volume Ventricular Function, Left
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