Dysregulation of Amino Acid, Lipid, and Acylpyruvate Metabolism in Idiopathic Intracranial Hypertension: A Non-targeted Case Control and Longitudinal Metabolomic Study

Background: Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure occurring predominantly in women with obesity. The pathogenesis is not understood. We have applied untargeted metabolomic analysis using ultrahigh-performance liquid chromatography–mass spectro...

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Veröffentlicht in:	Journal of proteome research 2023-04, Vol.22 (4), p.1127-1137
Hauptverfasser:	Alimajstorovic, Zerin, Mollan, Susan P., Grech, Olivia, Mitchell, James L., Yiangou, Andreas, Thaller, Mark, Lyons, Hannah, Sassani, Matilde, Seneviratne, Senali, Hancox, Thomas, Jankevics, Andris, Najdekr, Lukáš, Dunn, Warwick, Sinclair, Alexandra J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids Case-Control Studies Female Humans Lipids Pseudotumor Cerebri - cerebrospinal fluid Pseudotumor Cerebri - complications Weight Loss
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