Nickel allergy is associated with a broad spectrum cytokine response

Background Nickel‐induced proliferation or cytokine release by peripheral blood mononuclear cells may be used for in vitro diagnosis of nickel allergy. Objectives Aim of this study was to explore the nickel‐specific cytokine profile to further elucidate the pathogenesis of nickel allergic contact de...

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Veröffentlicht in:	Contact dermatitis 2023-01, Vol.88 (1), p.10-17
Hauptverfasser:	De Graaf, Niels P. J., Roffel, Sanne, Gibbs, Susan, Kleverlaan, Cees J., Lopez Gonzalez, Marta, Rustemeyer, Thomas, Feilzer, Albert J., Bontkes, Hetty J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens Allergies allergy Antigen presentation Biomarkers Cell culture Cell proliferation Chemokines Contact dermatitis Cytokines Cytokines - analysis Dermatitis, Allergic Contact - diagnosis Eczema Humans IL‐5 Immune response Interferon Interleukin-5 Leukocytes, Mononuclear Lymphocytes Nickel Nickel - adverse effects Original Peripheral blood mononuclear cells Tumor necrosis factor
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