RNAget: an API to securely retrieve RNA quantifications

Abstract Summary Large-scale sharing of genomic quantification data requires standardized access interfaces. In this Global Alliance for Genomics and Health project, we developed RNAget, an API for secure access to genomic quantification data in matrix form. RNAget provides for slicing matrices to e...

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Veröffentlicht in:Bioinformatics (Oxford, England) England), 2023-04, Vol.39 (4)
Hauptverfasser: Upchurch, Sean, Palumbo, Emilio, Adams, Jeremy, Bujold, David, Bourque, Guillaume, Nedzel, Jared, Graham, Keenan, Kagda, Meenakshi S, Assis, Pedro, Hitz, Benjamin, Righi, Emilio, Guigó, Roderic, Wold, Barbara J
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container_issue 4
container_start_page
container_title Bioinformatics (Oxford, England)
container_volume 39
creator Upchurch, Sean
Palumbo, Emilio
Adams, Jeremy
Bujold, David
Bourque, Guillaume
Nedzel, Jared
Graham, Keenan
Kagda, Meenakshi S
Assis, Pedro
Hitz, Benjamin
Righi, Emilio
Guigó, Roderic
Wold, Barbara J
description Abstract Summary Large-scale sharing of genomic quantification data requires standardized access interfaces. In this Global Alliance for Genomics and Health project, we developed RNAget, an API for secure access to genomic quantification data in matrix form. RNAget provides for slicing matrices to extract desired subsets of data and is applicable to all expression matrix-format data, including RNA sequencing and microarrays. Further, it generalizes to quantification matrices of other sequence-based genomics such as ATAC-seq and ChIP-seq. Availability and implementation https://ga4gh-rnaseq.github.io/schema/docs/index.html.
doi_str_mv 10.1093/bioinformatics/btad126
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subjects Applications Note
Genome
Genomics
RNA
Sequence Analysis, RNA
Software
title RNAget: an API to securely retrieve RNA quantifications
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