RNAget: an API to securely retrieve RNA quantifications
Abstract Summary Large-scale sharing of genomic quantification data requires standardized access interfaces. In this Global Alliance for Genomics and Health project, we developed RNAget, an API for secure access to genomic quantification data in matrix form. RNAget provides for slicing matrices to e...
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Veröffentlicht in: | Bioinformatics (Oxford, England) England), 2023-04, Vol.39 (4) |
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container_title | Bioinformatics (Oxford, England) |
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creator | Upchurch, Sean Palumbo, Emilio Adams, Jeremy Bujold, David Bourque, Guillaume Nedzel, Jared Graham, Keenan Kagda, Meenakshi S Assis, Pedro Hitz, Benjamin Righi, Emilio Guigó, Roderic Wold, Barbara J |
description | Abstract
Summary
Large-scale sharing of genomic quantification data requires standardized access interfaces. In this Global Alliance for Genomics and Health project, we developed RNAget, an API for secure access to genomic quantification data in matrix form. RNAget provides for slicing matrices to extract desired subsets of data and is applicable to all expression matrix-format data, including RNA sequencing and microarrays. Further, it generalizes to quantification matrices of other sequence-based genomics such as ATAC-seq and ChIP-seq.
Availability and implementation
https://ga4gh-rnaseq.github.io/schema/docs/index.html. |
doi_str_mv | 10.1093/bioinformatics/btad126 |
format | Article |
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Summary
Large-scale sharing of genomic quantification data requires standardized access interfaces. In this Global Alliance for Genomics and Health project, we developed RNAget, an API for secure access to genomic quantification data in matrix form. RNAget provides for slicing matrices to extract desired subsets of data and is applicable to all expression matrix-format data, including RNA sequencing and microarrays. Further, it generalizes to quantification matrices of other sequence-based genomics such as ATAC-seq and ChIP-seq.
Availability and implementation
https://ga4gh-rnaseq.github.io/schema/docs/index.html.</description><identifier>ISSN: 1367-4811</identifier><identifier>ISSN: 1367-4803</identifier><identifier>EISSN: 1367-4811</identifier><identifier>DOI: 10.1093/bioinformatics/btad126</identifier><identifier>PMID: 36897015</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Applications Note ; Genome ; Genomics ; RNA ; Sequence Analysis, RNA ; Software</subject><ispartof>Bioinformatics (Oxford, England), 2023-04, Vol.39 (4)</ispartof><rights>The Author(s) 2023. Published by Oxford University Press. 2023</rights><rights>The Author(s) 2023. Published by Oxford University Press.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c457t-3230ec2fa5d825680cb30babefc3dbe23f913ffd60cc9e56bcf0993464efd6c93</citedby><cites>FETCH-LOGICAL-c457t-3230ec2fa5d825680cb30babefc3dbe23f913ffd60cc9e56bcf0993464efd6c93</cites><orcidid>0000-0002-3119-8975 ; 0000-0002-3933-9656 ; 0000-0003-3361-3594</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081869/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081869/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,1598,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36897015$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Boeva, Valentina</contributor><creatorcontrib>Upchurch, Sean</creatorcontrib><creatorcontrib>Palumbo, Emilio</creatorcontrib><creatorcontrib>Adams, Jeremy</creatorcontrib><creatorcontrib>Bujold, David</creatorcontrib><creatorcontrib>Bourque, Guillaume</creatorcontrib><creatorcontrib>Nedzel, Jared</creatorcontrib><creatorcontrib>Graham, Keenan</creatorcontrib><creatorcontrib>Kagda, Meenakshi S</creatorcontrib><creatorcontrib>Assis, Pedro</creatorcontrib><creatorcontrib>Hitz, Benjamin</creatorcontrib><creatorcontrib>Righi, Emilio</creatorcontrib><creatorcontrib>Guigó, Roderic</creatorcontrib><creatorcontrib>Wold, Barbara J</creatorcontrib><creatorcontrib>GA4GH RNA-Seq Task Team</creatorcontrib><title>RNAget: an API to securely retrieve RNA quantifications</title><title>Bioinformatics (Oxford, England)</title><addtitle>Bioinformatics</addtitle><description>Abstract
Summary
Large-scale sharing of genomic quantification data requires standardized access interfaces. In this Global Alliance for Genomics and Health project, we developed RNAget, an API for secure access to genomic quantification data in matrix form. RNAget provides for slicing matrices to extract desired subsets of data and is applicable to all expression matrix-format data, including RNA sequencing and microarrays. Further, it generalizes to quantification matrices of other sequence-based genomics such as ATAC-seq and ChIP-seq.
Availability and implementation
https://ga4gh-rnaseq.github.io/schema/docs/index.html.</description><subject>Applications Note</subject><subject>Genome</subject><subject>Genomics</subject><subject>RNA</subject><subject>Sequence Analysis, RNA</subject><subject>Software</subject><issn>1367-4811</issn><issn>1367-4803</issn><issn>1367-4811</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>TOX</sourceid><sourceid>EIF</sourceid><recordid>eNqNkE9PAjEQxRujEUS_AtmjF6Td7na3Xgwh_iEhaoyem253ijW7W2i7JHx7l4AEbp5mMvOb9yYPoSHBdwRzOi6MNY22rpbBKD8ugixJzM5Qn1CWjZKckPOjvoeuvP_BGKc4ZZeoR1nOM0zSPso-XicLCPeRbKLJ-ywKNvKgWgfVJnIQnIE1RB0TrVrZBKON6gxt46_RhZaVh5t9HaCvp8fP6cto_vY8m07mI5WkWRjRmGJQsZZpmccpy7EqKC5kAVrRsoCYak6o1iXDSnFIWaE05pwmLIFuqDgdoIed7rItaigVNMHJSiydqaXbCCuNON005lss7FoQjHOSs63C7V7B2VULPojaeAVVJRuwrRdxljPMGUvyDmU7VDnrvQN98CFYbGMXp7GLfezd4fD4y8PZX84dQHaAbZf_Ff0FGRuXEw</recordid><startdate>20230403</startdate><enddate>20230403</enddate><creator>Upchurch, Sean</creator><creator>Palumbo, Emilio</creator><creator>Adams, Jeremy</creator><creator>Bujold, David</creator><creator>Bourque, Guillaume</creator><creator>Nedzel, Jared</creator><creator>Graham, Keenan</creator><creator>Kagda, Meenakshi S</creator><creator>Assis, Pedro</creator><creator>Hitz, Benjamin</creator><creator>Righi, Emilio</creator><creator>Guigó, Roderic</creator><creator>Wold, Barbara J</creator><general>Oxford University Press</general><scope>TOX</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-3119-8975</orcidid><orcidid>https://orcid.org/0000-0002-3933-9656</orcidid><orcidid>https://orcid.org/0000-0003-3361-3594</orcidid></search><sort><creationdate>20230403</creationdate><title>RNAget: an API to securely retrieve RNA quantifications</title><author>Upchurch, Sean ; Palumbo, Emilio ; Adams, Jeremy ; Bujold, David ; Bourque, Guillaume ; Nedzel, Jared ; Graham, Keenan ; Kagda, Meenakshi S ; Assis, Pedro ; Hitz, Benjamin ; Righi, Emilio ; Guigó, Roderic ; Wold, Barbara J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c457t-3230ec2fa5d825680cb30babefc3dbe23f913ffd60cc9e56bcf0993464efd6c93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Applications Note</topic><topic>Genome</topic><topic>Genomics</topic><topic>RNA</topic><topic>Sequence Analysis, RNA</topic><topic>Software</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Upchurch, Sean</creatorcontrib><creatorcontrib>Palumbo, Emilio</creatorcontrib><creatorcontrib>Adams, Jeremy</creatorcontrib><creatorcontrib>Bujold, David</creatorcontrib><creatorcontrib>Bourque, Guillaume</creatorcontrib><creatorcontrib>Nedzel, Jared</creatorcontrib><creatorcontrib>Graham, Keenan</creatorcontrib><creatorcontrib>Kagda, Meenakshi S</creatorcontrib><creatorcontrib>Assis, Pedro</creatorcontrib><creatorcontrib>Hitz, Benjamin</creatorcontrib><creatorcontrib>Righi, Emilio</creatorcontrib><creatorcontrib>Guigó, Roderic</creatorcontrib><creatorcontrib>Wold, Barbara J</creatorcontrib><creatorcontrib>GA4GH RNA-Seq Task Team</creatorcontrib><collection>Oxford Journals Open Access Collection</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Bioinformatics (Oxford, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Upchurch, Sean</au><au>Palumbo, Emilio</au><au>Adams, Jeremy</au><au>Bujold, David</au><au>Bourque, Guillaume</au><au>Nedzel, Jared</au><au>Graham, Keenan</au><au>Kagda, Meenakshi S</au><au>Assis, Pedro</au><au>Hitz, Benjamin</au><au>Righi, Emilio</au><au>Guigó, Roderic</au><au>Wold, Barbara J</au><au>Boeva, Valentina</au><aucorp>GA4GH RNA-Seq Task Team</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>RNAget: an API to securely retrieve RNA quantifications</atitle><jtitle>Bioinformatics (Oxford, England)</jtitle><addtitle>Bioinformatics</addtitle><date>2023-04-03</date><risdate>2023</risdate><volume>39</volume><issue>4</issue><issn>1367-4811</issn><issn>1367-4803</issn><eissn>1367-4811</eissn><abstract>Abstract
Summary
Large-scale sharing of genomic quantification data requires standardized access interfaces. In this Global Alliance for Genomics and Health project, we developed RNAget, an API for secure access to genomic quantification data in matrix form. RNAget provides for slicing matrices to extract desired subsets of data and is applicable to all expression matrix-format data, including RNA sequencing and microarrays. Further, it generalizes to quantification matrices of other sequence-based genomics such as ATAC-seq and ChIP-seq.
Availability and implementation
https://ga4gh-rnaseq.github.io/schema/docs/index.html.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>36897015</pmid><doi>10.1093/bioinformatics/btad126</doi><orcidid>https://orcid.org/0000-0002-3119-8975</orcidid><orcidid>https://orcid.org/0000-0002-3933-9656</orcidid><orcidid>https://orcid.org/0000-0003-3361-3594</orcidid><oa>free_for_read</oa></addata></record> |
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source | Oxford Journals Open Access Collection; MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
subjects | Applications Note Genome Genomics RNA Sequence Analysis, RNA Software |
title | RNAget: an API to securely retrieve RNA quantifications |
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