Type IV collagen α5 chain promotes luminal breast cancer progression through c-Myc-driven glycolysis

ABSTRACT Cancer cell metabolism reprogramming is one of the hallmarks of cancer. Cancer cells preferentially utilize aerobic glycolysis, which is regulated by activated oncogenes and the tumor microenvironment. Extracellular matrix (ECM) in the tumor microenvironment, including the basement membrane...

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Veröffentlicht in:	Journal of molecular cell biology 2023-03, Vol.14 (10)
Hauptverfasser:	Wu, Yuexin, Liu, Xiangming, Zhu, Yue, Qiao, Yuemei, Gao, Yuan, Chen, Jianfeng, Ge, Gaoxiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast - metabolism Breast Neoplasms - metabolism Cell Proliferation Collagen Type IV - metabolism Female Glycolysis Humans Tumor Microenvironment
Online-Zugang:	Volltext
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