Atypical Presentation of Sjogren's Syndrome With Chronic Urticaria: A Case Report and Literature Review
We present a case of a 26-year-old female with a history of 6-8 months of recurrent severe allergic reactions with anaphylaxis who presented with bilateral shoulder arthralgia and inflammatory arthritis of the right hand involving metacarpophalangeal joints (MCP). Physical examination was significan...
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Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2023-03, Vol.15 (3), p.e35809 |
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description | We present a case of a 26-year-old female with a history of 6-8 months of recurrent severe allergic reactions with anaphylaxis who presented with bilateral shoulder arthralgia and inflammatory arthritis of the right hand involving metacarpophalangeal joints (MCP). Physical examination was significant for tenderness in shoulder and knee joints, swelling, warmth, and tenderness involving MCP joints of the right hand. Schirmer's test was positive in both eyes. Further workup revealed positive antinuclear antibody (ANA) (speckled pattern), anti-Ro antibodies, and elevated inflammatory markers including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). The patient was diagnosed with Sjogren's syndrome and was started on methotrexate once weekly and hydroxychloroquine with significant improvement in the symptoms. Also, we review the literature describing the association between chronic urticaria and rheumatological diseases. This case highlights the varied presentation of rheumatological diseases. |
doi_str_mv | 10.7759/cureus.35809 |
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Physical examination was significant for tenderness in shoulder and knee joints, swelling, warmth, and tenderness involving MCP joints of the right hand. Schirmer's test was positive in both eyes. Further workup revealed positive antinuclear antibody (ANA) (speckled pattern), anti-Ro antibodies, and elevated inflammatory markers including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). The patient was diagnosed with Sjogren's syndrome and was started on methotrexate once weekly and hydroxychloroquine with significant improvement in the symptoms. Also, we review the literature describing the association between chronic urticaria and rheumatological diseases. This case highlights the varied presentation of rheumatological diseases.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.35809</identifier><identifier>PMID: 37033579</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Abdomen ; Anaphylaxis ; Antibodies ; Antigens ; Arthritis ; Autoimmune diseases ; Case reports ; Celiac disease ; Exocrine glands ; Internal Medicine ; Literature reviews ; Patients ; Rheumatology ; Steroids ; Urticaria</subject><ispartof>Curēus (Palo Alto, CA), 2023-03, Vol.15 (3), p.e35809</ispartof><rights>Copyright © 2023, Ahmad et al.</rights><rights>Copyright © 2023, Ahmad et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2023, Ahmad et al. 2023 Ahmad et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c267t-aa9bd5a75f1c7b4a6d93932d30e9c012fc467ec0f7bc9fdda2fa06e01c8c59fa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075139/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075139/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37033579$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ahmad, Umair</creatorcontrib><creatorcontrib>Waseem, Tania</creatorcontrib><creatorcontrib>Logee, Kristin</creatorcontrib><title>Atypical Presentation of Sjogren's Syndrome With Chronic Urticaria: A Case Report and Literature Review</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>We present a case of a 26-year-old female with a history of 6-8 months of recurrent severe allergic reactions with anaphylaxis who presented with bilateral shoulder arthralgia and inflammatory arthritis of the right hand involving metacarpophalangeal joints (MCP). Physical examination was significant for tenderness in shoulder and knee joints, swelling, warmth, and tenderness involving MCP joints of the right hand. Schirmer's test was positive in both eyes. Further workup revealed positive antinuclear antibody (ANA) (speckled pattern), anti-Ro antibodies, and elevated inflammatory markers including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). The patient was diagnosed with Sjogren's syndrome and was started on methotrexate once weekly and hydroxychloroquine with significant improvement in the symptoms. Also, we review the literature describing the association between chronic urticaria and rheumatological diseases. 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subjects | Abdomen Anaphylaxis Antibodies Antigens Arthritis Autoimmune diseases Case reports Celiac disease Exocrine glands Internal Medicine Literature reviews Patients Rheumatology Steroids Urticaria |
title | Atypical Presentation of Sjogren's Syndrome With Chronic Urticaria: A Case Report and Literature Review |
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