Atypical Presentation of Sjogren's Syndrome With Chronic Urticaria: A Case Report and Literature Review

We present a case of a 26-year-old female with a history of 6-8 months of recurrent severe allergic reactions with anaphylaxis who presented with bilateral shoulder arthralgia and inflammatory arthritis of the right hand involving metacarpophalangeal joints (MCP). Physical examination was significan...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2023-03, Vol.15 (3), p.e35809
Hauptverfasser: Ahmad, Umair, Waseem, Tania, Logee, Kristin
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue 3
container_start_page e35809
container_title Curēus (Palo Alto, CA)
container_volume 15
creator Ahmad, Umair
Waseem, Tania
Logee, Kristin
description We present a case of a 26-year-old female with a history of 6-8 months of recurrent severe allergic reactions with anaphylaxis who presented with bilateral shoulder arthralgia and inflammatory arthritis of the right hand involving metacarpophalangeal joints (MCP). Physical examination was significant for tenderness in shoulder and knee joints, swelling, warmth, and tenderness involving MCP joints of the right hand. Schirmer's test was positive in both eyes. Further workup revealed positive antinuclear antibody (ANA) (speckled pattern), anti-Ro antibodies, and elevated inflammatory markers including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). The patient was diagnosed with Sjogren's syndrome and was started on methotrexate once weekly and hydroxychloroquine with significant improvement in the symptoms. Also, we review the literature describing the association between chronic urticaria and rheumatological diseases. This case highlights the varied presentation of rheumatological diseases.
doi_str_mv 10.7759/cureus.35809
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10075139</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2807826332</sourcerecordid><originalsourceid>FETCH-LOGICAL-c267t-aa9bd5a75f1c7b4a6d93932d30e9c012fc467ec0f7bc9fdda2fa06e01c8c59fa3</originalsourceid><addsrcrecordid>eNpVUV1LKzEQDaKoVN98lsB98OVWJ0l3s_FFSrl-QEHxAx_DNJu0Ke2mJlml_97VekWfZpg5c84ZDiFHDE6lLNSZaaNt06koKlBbZJ-zsupXrBps_-j3yGFKcwBgIDlI2CV7QoIQhVT7ZDrM65U3uKB30SbbZMw-NDQ4-jAP02ibk0Qf1k0dw9LSZ59ndDSLofGGPsXc3UWP53RIR5gsvberEDPFpqZjn23E3Lnrpq_evh2QHYeLZA-_ao88Xf57HF33x7dXN6PhuG94KXMfUU3qAmXhmJGTAZa1EkrwWoBVBhh3ZlBKa8DJiVGurpE7hNICM5UplEPRIxcb3lU7WdradB9FXOhV9EuMax3Q69-bxs_0NLxqBiAL1on1yJ8vhhheWpuynoc2Np1pzSuQFS-F4B3q7wZlYkgpWvctwUB_RKM30ejPaDr48U9b3-D_QYh35vqNgg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2807826332</pqid></control><display><type>article</type><title>Atypical Presentation of Sjogren's Syndrome With Chronic Urticaria: A Case Report and Literature Review</title><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Ahmad, Umair ; Waseem, Tania ; Logee, Kristin</creator><creatorcontrib>Ahmad, Umair ; Waseem, Tania ; Logee, Kristin</creatorcontrib><description>We present a case of a 26-year-old female with a history of 6-8 months of recurrent severe allergic reactions with anaphylaxis who presented with bilateral shoulder arthralgia and inflammatory arthritis of the right hand involving metacarpophalangeal joints (MCP). Physical examination was significant for tenderness in shoulder and knee joints, swelling, warmth, and tenderness involving MCP joints of the right hand. Schirmer's test was positive in both eyes. Further workup revealed positive antinuclear antibody (ANA) (speckled pattern), anti-Ro antibodies, and elevated inflammatory markers including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). The patient was diagnosed with Sjogren's syndrome and was started on methotrexate once weekly and hydroxychloroquine with significant improvement in the symptoms. Also, we review the literature describing the association between chronic urticaria and rheumatological diseases. This case highlights the varied presentation of rheumatological diseases.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.35809</identifier><identifier>PMID: 37033579</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Abdomen ; Anaphylaxis ; Antibodies ; Antigens ; Arthritis ; Autoimmune diseases ; Case reports ; Celiac disease ; Exocrine glands ; Internal Medicine ; Literature reviews ; Patients ; Rheumatology ; Steroids ; Urticaria</subject><ispartof>Curēus (Palo Alto, CA), 2023-03, Vol.15 (3), p.e35809</ispartof><rights>Copyright © 2023, Ahmad et al.</rights><rights>Copyright © 2023, Ahmad et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2023, Ahmad et al. 2023 Ahmad et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c267t-aa9bd5a75f1c7b4a6d93932d30e9c012fc467ec0f7bc9fdda2fa06e01c8c59fa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075139/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075139/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37033579$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ahmad, Umair</creatorcontrib><creatorcontrib>Waseem, Tania</creatorcontrib><creatorcontrib>Logee, Kristin</creatorcontrib><title>Atypical Presentation of Sjogren's Syndrome With Chronic Urticaria: A Case Report and Literature Review</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>We present a case of a 26-year-old female with a history of 6-8 months of recurrent severe allergic reactions with anaphylaxis who presented with bilateral shoulder arthralgia and inflammatory arthritis of the right hand involving metacarpophalangeal joints (MCP). Physical examination was significant for tenderness in shoulder and knee joints, swelling, warmth, and tenderness involving MCP joints of the right hand. Schirmer's test was positive in both eyes. Further workup revealed positive antinuclear antibody (ANA) (speckled pattern), anti-Ro antibodies, and elevated inflammatory markers including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). The patient was diagnosed with Sjogren's syndrome and was started on methotrexate once weekly and hydroxychloroquine with significant improvement in the symptoms. Also, we review the literature describing the association between chronic urticaria and rheumatological diseases. This case highlights the varied presentation of rheumatological diseases.</description><subject>Abdomen</subject><subject>Anaphylaxis</subject><subject>Antibodies</subject><subject>Antigens</subject><subject>Arthritis</subject><subject>Autoimmune diseases</subject><subject>Case reports</subject><subject>Celiac disease</subject><subject>Exocrine glands</subject><subject>Internal Medicine</subject><subject>Literature reviews</subject><subject>Patients</subject><subject>Rheumatology</subject><subject>Steroids</subject><subject>Urticaria</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpVUV1LKzEQDaKoVN98lsB98OVWJ0l3s_FFSrl-QEHxAx_DNJu0Ke2mJlml_97VekWfZpg5c84ZDiFHDE6lLNSZaaNt06koKlBbZJ-zsupXrBps_-j3yGFKcwBgIDlI2CV7QoIQhVT7ZDrM65U3uKB30SbbZMw-NDQ4-jAP02ibk0Qf1k0dw9LSZ59ndDSLofGGPsXc3UWP53RIR5gsvberEDPFpqZjn23E3Lnrpq_evh2QHYeLZA-_ao88Xf57HF33x7dXN6PhuG94KXMfUU3qAmXhmJGTAZa1EkrwWoBVBhh3ZlBKa8DJiVGurpE7hNICM5UplEPRIxcb3lU7WdradB9FXOhV9EuMax3Q69-bxs_0NLxqBiAL1on1yJ8vhhheWpuynoc2Np1pzSuQFS-F4B3q7wZlYkgpWvctwUB_RKM30ejPaDr48U9b3-D_QYh35vqNgg</recordid><startdate>20230306</startdate><enddate>20230306</enddate><creator>Ahmad, Umair</creator><creator>Waseem, Tania</creator><creator>Logee, Kristin</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>5PM</scope></search><sort><creationdate>20230306</creationdate><title>Atypical Presentation of Sjogren's Syndrome With Chronic Urticaria: A Case Report and Literature Review</title><author>Ahmad, Umair ; Waseem, Tania ; Logee, Kristin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c267t-aa9bd5a75f1c7b4a6d93932d30e9c012fc467ec0f7bc9fdda2fa06e01c8c59fa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Abdomen</topic><topic>Anaphylaxis</topic><topic>Antibodies</topic><topic>Antigens</topic><topic>Arthritis</topic><topic>Autoimmune diseases</topic><topic>Case reports</topic><topic>Celiac disease</topic><topic>Exocrine glands</topic><topic>Internal Medicine</topic><topic>Literature reviews</topic><topic>Patients</topic><topic>Rheumatology</topic><topic>Steroids</topic><topic>Urticaria</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ahmad, Umair</creatorcontrib><creatorcontrib>Waseem, Tania</creatorcontrib><creatorcontrib>Logee, Kristin</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ahmad, Umair</au><au>Waseem, Tania</au><au>Logee, Kristin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Atypical Presentation of Sjogren's Syndrome With Chronic Urticaria: A Case Report and Literature Review</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2023-03-06</date><risdate>2023</risdate><volume>15</volume><issue>3</issue><spage>e35809</spage><pages>e35809-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>We present a case of a 26-year-old female with a history of 6-8 months of recurrent severe allergic reactions with anaphylaxis who presented with bilateral shoulder arthralgia and inflammatory arthritis of the right hand involving metacarpophalangeal joints (MCP). Physical examination was significant for tenderness in shoulder and knee joints, swelling, warmth, and tenderness involving MCP joints of the right hand. Schirmer's test was positive in both eyes. Further workup revealed positive antinuclear antibody (ANA) (speckled pattern), anti-Ro antibodies, and elevated inflammatory markers including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). The patient was diagnosed with Sjogren's syndrome and was started on methotrexate once weekly and hydroxychloroquine with significant improvement in the symptoms. Also, we review the literature describing the association between chronic urticaria and rheumatological diseases. This case highlights the varied presentation of rheumatological diseases.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>37033579</pmid><doi>10.7759/cureus.35809</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2168-8184
ispartof Curēus (Palo Alto, CA), 2023-03, Vol.15 (3), p.e35809
issn 2168-8184
2168-8184
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10075139
source PubMed Central Open Access; PubMed Central
subjects Abdomen
Anaphylaxis
Antibodies
Antigens
Arthritis
Autoimmune diseases
Case reports
Celiac disease
Exocrine glands
Internal Medicine
Literature reviews
Patients
Rheumatology
Steroids
Urticaria
title Atypical Presentation of Sjogren's Syndrome With Chronic Urticaria: A Case Report and Literature Review
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T09%3A31%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Atypical%20Presentation%20of%20Sjogren's%20Syndrome%20With%20Chronic%20Urticaria:%20A%20Case%20Report%20and%20Literature%20Review&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Ahmad,%20Umair&rft.date=2023-03-06&rft.volume=15&rft.issue=3&rft.spage=e35809&rft.pages=e35809-&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.35809&rft_dat=%3Cproquest_pubme%3E2807826332%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2807826332&rft_id=info:pmid/37033579&rfr_iscdi=true