T790M and Acquired Resistance of Epidermal Growth Factor Receptor to Tyrosine Kinase Inhibitors in Patients with Lung Adenocarcinoma

Activating mutations in the epidermal growth factor receptor (EGFR) are initially responsive to tyrosine kinase inhibitors (TKIs), but responses to TKIs is not permanent and drug resistance eventually happens for almost all patients. Subsequent studies found different resistance mechanisms, among wh...

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Veröffentlicht in:	Tanaffus 2022-03, Vol.21 (3), p.376-383
Hauptverfasser:	Mirtavoos-Mahyari, Hanifeh, Abbasi Dezfouli, Azizollah, Esfahani-Monfared, Zahra, Khosravi, Adnan, Seifi, Sharareh, Sheikhy, Kambiz
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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