Primary Squamous Cell Carcinoma of Gallbladder With Hepatic Invasion
Squamous cell carcinoma of the gallbladder is a profoundly rare tumor. It is one of the most aggressive and deadly forms of gallbladder cancer, often being diagnosed at a later stage. There are no definitive risk factors described for this specific type of gallbladder tumor when compared to other fo...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2023-03, Vol.15 (3), p.e35795 |
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| creator | Willson, Conner M Barsoum, Nathalie Khan, Mustafa Tamim Alam Rushton, Jennifer |
| description | Squamous cell carcinoma of the gallbladder is a profoundly rare tumor. It is one of the most aggressive and deadly forms of gallbladder cancer, often being diagnosed at a later stage. There are no definitive risk factors described for this specific type of gallbladder tumor when compared to other forms of gallbladder carcinoma. This case is regarding a 64-year-old female who was found to have primary squamous cell carcinoma of the gallbladder during an attempted cholecystectomy. Her tumor was found to have invaded her liver. The tumor displayed characteristic qualities of a pure squamous cell carcinoma and was positive for CK7 and p63 upon pathological analysis. Best results for treatment for this condition are achieved via R0 resection. Adjuvant therapy with chemoradiation has not been well-defined nor very effective in prior cases. |
| doi_str_mv | 10.7759/cureus.35795 |
| format | Article |
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It is one of the most aggressive and deadly forms of gallbladder cancer, often being diagnosed at a later stage. There are no definitive risk factors described for this specific type of gallbladder tumor when compared to other forms of gallbladder carcinoma. This case is regarding a 64-year-old female who was found to have primary squamous cell carcinoma of the gallbladder during an attempted cholecystectomy. Her tumor was found to have invaded her liver. The tumor displayed characteristic qualities of a pure squamous cell carcinoma and was positive for CK7 and p63 upon pathological analysis. Best results for treatment for this condition are achieved via R0 resection. Adjuvant therapy with chemoradiation has not been well-defined nor very effective in prior cases.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.35795</identifier><identifier>PMID: 37025738</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Abdomen ; Antigens ; Cancer ; Chemotherapy ; Cytokeratin ; Females ; Gallbladder ; Gallbladder cancer ; Gallbladder diseases ; Gallstones ; General Surgery ; Hemorrhage ; Liver ; Medical imaging ; Medical prognosis ; Metastasis ; Oncology ; Pathology ; Radiation ; Squamous cell carcinoma ; Surgery ; White people</subject><ispartof>Curēus (Palo Alto, CA), 2023-03, Vol.15 (3), p.e35795</ispartof><rights>Copyright © 2023, Willson et al.</rights><rights>Copyright © 2023, Willson et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2023, Willson et al. 2023 Willson et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c267t-797ee6697f44a16f7b61979dbe4af117e897a6f7d5e1d979e2970ad39e0bc7ca3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072881/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072881/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37025738$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Willson, Conner M</creatorcontrib><creatorcontrib>Barsoum, Nathalie</creatorcontrib><creatorcontrib>Khan, Mustafa Tamim Alam</creatorcontrib><creatorcontrib>Rushton, Jennifer</creatorcontrib><title>Primary Squamous Cell Carcinoma of Gallbladder With Hepatic Invasion</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Squamous cell carcinoma of the gallbladder is a profoundly rare tumor. It is one of the most aggressive and deadly forms of gallbladder cancer, often being diagnosed at a later stage. There are no definitive risk factors described for this specific type of gallbladder tumor when compared to other forms of gallbladder carcinoma. This case is regarding a 64-year-old female who was found to have primary squamous cell carcinoma of the gallbladder during an attempted cholecystectomy. Her tumor was found to have invaded her liver. The tumor displayed characteristic qualities of a pure squamous cell carcinoma and was positive for CK7 and p63 upon pathological analysis. Best results for treatment for this condition are achieved via R0 resection. 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| source | PubMed Central Open Access; PubMed Central |
| subjects | Abdomen Antigens Cancer Chemotherapy Cytokeratin Females Gallbladder Gallbladder cancer Gallbladder diseases Gallstones General Surgery Hemorrhage Liver Medical imaging Medical prognosis Metastasis Oncology Pathology Radiation Squamous cell carcinoma Surgery White people |
| title | Primary Squamous Cell Carcinoma of Gallbladder With Hepatic Invasion |
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