Genomic ALK alterations in primary and relapsed neuroblastoma

Background Genomic alterations of the anaplastic lymphoma kinase gene ( ALK ) occur recurrently in neuroblastoma, a pediatric malignancy of the sympathetic nervous system. However, information on their development over time has remained sparse. Methods ALK alterations were assessed in neuroblastomas...

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Veröffentlicht in:	British journal of cancer 2023-04, Vol.128 (8), p.1559-1571
Hauptverfasser:	Rosswog, Carolina, Fassunke, Jana, Ernst, Angela, Schömig-Markiefka, Birgid, Merkelbach-Bruse, Sabine, Bartenhagen, Christoph, Cartolano, Maria, Ackermann, Sandra, Theissen, Jessica, Blattner-Johnson, Mirjam, Jones, Barbara, Schramm, Kathrin, Altmüller, Janine, Nürnberg, Peter, Ortmann, Monika, Berthold, Frank, Peifer, Martin, Büttner, Reinhard, Westermann, Frank, Schulte, Johannes H., Simon, Thorsten, Hero, Barbara, Fischer, Matthias
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/68 692/4028/67/2332 Anaplastic Lymphoma Kinase - genetics Biomedical and Life Sciences Biomedicine Cancer Research Child Diagnosis Drug Resistance Epidemiology Genomics Humans Kinases Malignancy Molecular Medicine Mutation Neoplasm Recurrence, Local - genetics Neuroblastoma Neuroblastoma - genetics Neuroblastoma - pathology Oncology Patients Pediatrics Protein-tyrosine kinase Receptor Protein-Tyrosine Kinases - genetics Sympathetic nervous system
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