Supplementation-induced change in muscle carnosine is paralleled by changes in muscle metabolism, protein glycation and reactive carbonyl species sequestering

Carnosine is a performance-enhancing food supplement with a potential to modulate muscle energy metabolism and toxic metabolites disposal. In this study we explored interrelations between carnosine supplementation (2 g/day, 12 weeks) induced effects on carnosine muscle loading and parallel changes i...

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Veröffentlicht in:	Physiological research 2023, Vol.72 (1), p.87-97
Hauptverfasser:	Schön, M, Just, I, Krumpolec, P, Blažíček, P, Valkovič, L, Aldini, G, Tsai, C-L, De Courten, B, Krššák, M, Ukropcová, B, Ukropec, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Albumin Body composition Body mass index Body weight Calorimetry Carbonyl compounds Carnosine Carnosine - metabolism Carnosine - pharmacology Diabetes Dietary Supplements Energy Energy expenditure Energy metabolism Exercise Food Glucose Glucose tolerance Glycosylation Humans Insulin Lifestyles Magnetic resonance imaging Magnetic resonance spectroscopy Maillard Reaction Mass spectroscopy Metabolic disorders Metabolites Middle age Muscle, Skeletal - metabolism Musculoskeletal system Obesity Overweight Phosphocreatine Phosphocreatine - metabolism Physical activity Physical fitness Physical training Propionaldehyde Protein turnover Proteins Weight control
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