Human IFT-A complex structures provide molecular insights into ciliary transport

Intraflagellar transport (IFT) complexes, IFT-A and IFT-B, form bidirectional trains that move along the axonemal microtubules and are essential for assembling and maintaining cilia. Mutations in IFT subunits lead to numerous ciliopathies involving multiple tissues. However, how IFT complexes assemb...

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Veröffentlicht in:	Cell research 2023-04, Vol.33 (4), p.288-298
Hauptverfasser:	Jiang, Meiqin, Palicharla, Vivek Reddy, Miller, Darcie, Hwang, Sun-Hee, Zhu, Hanwen, Hixson, Patricia, Mukhopadhyay, Saikat, Sun, Ji
Format:	Artikel
Sprache:	eng
Schlagworte:	101/28 14 14/1 631/535/1258/1259 631/80/128/1383 82 82/80 82/83 Biological Transport Biomedical and Life Sciences Cargo transportation Cell Biology Cilia Cilia - metabolism Complex formation Disease Humans Life Sciences Microtubules Mutation Protein Transport Proteins
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