Development and validation of a liquid chromatographic-tandem mass spectrometric assay for the quantification of cabotegravir and rilpivirine from dried blood spots

Dried blood spots (DBS) have been utilized as a blood plasma alternative for therapeutic drug monitoring and pharmacologic analysis. There are analytical and physiochemical considerations in bridging drug concentrations from plasma to DBS. Recently, the long-acting antiretroviral cabotegravir (CAB)...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2023-05, Vol.228, p.115307-115307, Article 115307
Hauptverfasser:	Weld, Ethel D., Parsons, Teresa L., Gollings, Ryann, McCauley, Marybeth, Grinsztejn, Beatriz, Landovitz, Raphael J., Marzinke, Mark A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cabotegravir Chromatography, Liquid - methods DBS Dried Blood Spot Testing - methods HIV HIV Infections - drug therapy HIV Infections - prevention & control Humans LC-MS Mass spectrometry Reproducibility of Results Rilpivirine Tandem Mass Spectrometry - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!