Malignant lesions of the caruncle

Caruncle malignancy is rare, but signs of disease can be easily missed by both patients and clinicians. There is significant potential for significant morbidity and even mortality from delayed diagnosis and treatment. Clinical features of primary malignant cancer include rapid growth, pigment deposi...

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Veröffentlicht in:Eye (London) 2023-04, Vol.37 (5), p.849-857
Hauptverfasser: Gounder, Pav, Selva, Dinesh, Rajak, Saul N.
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Selva, Dinesh
Rajak, Saul N.
description Caruncle malignancy is rare, but signs of disease can be easily missed by both patients and clinicians. There is significant potential for significant morbidity and even mortality from delayed diagnosis and treatment. Clinical features of primary malignant cancer include rapid growth, pigment deposition, ulcerated surface and bleeding. Malignant diagnoses include lymphoproliferative disease, basal cell carcinoma, squamous cell carcinoma, sebaceous carcinoma and malignant melanoma. Increased pigmentation is associated with melanoma, yellow coloured deposition with sebaceous carcinoma and a salmon-pink hue with lymphoproliferative disease. Treatment involves excision with margin control which may necessitate exenteration. Metastases to cervical and preauricular lymph nodes has been reported.
doi_str_mv 10.1038/s41433-022-02124-0
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subjects 692/1807/1482
692/699
Adenocarcinoma, Sebaceous - pathology
Basal cell carcinoma
Biopsy
Carcinoma, Basal Cell - pathology
Cell growth
Chemotherapy
Humans
Hyperplasia
Immunoproliferative diseases
Laboratory Medicine
Lymph nodes
Lymphatic system
Lymphocytes
Lymphoma
Malignancy
Medical diagnosis
Medicine
Medicine & Public Health
Melanoma
Melanoma - diagnosis
Melanoma - pathology
Melanoma - surgery
Metastases
Morbidity
Mortality
Ophthalmology
Pharmaceutical Sciences/Technology
Pigmentation
Radiation therapy
Review
Review Article
Sebaceous Gland Neoplasms - surgery
Skin cancer
Skin Neoplasms - diagnosis
Skin Neoplasms - pathology
Skin Neoplasms - surgery
Squamous cell carcinoma
Surgery
Surgical Oncology
title Malignant lesions of the caruncle
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