CCR7 Mediates Cell Invasion and Migration in Extrahepatic Cholangiocarcinoma by Inducing Epithelial-Mesenchymal Transition

The epithelial-mesenchymal transition (EMT) contributes to the metastatic cascade in various tumors. C-C chemokine receptor 7 (CCR7) interacts with its ligand, chemokine (C-C motif) ligand 19 (CCL19), to promote EMT. However, the association between EMT and CCR7 in extrahepatic cholangiocarcinoma (E...

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Veröffentlicht in:	Cancers 2023-03, Vol.15 (6), p.1878
Hauptverfasser:	Oba, Mitsunobu, Nakanishi, Yoshitsugu, Mitsuhashi, Tomoko, Sasaki, Katsunori, Hatanaka, Kanako C, Sasaki, Masako, Nange, Ayae, Okumura, Asami, Hayashi, Mariko, Yoshida, Yusuke, Nitta, Takeo, Ueno, Takashi, Yamada, Toru, Ono, Masato, Kuwabara, Shota, Okamura, Keisuke, Tsuchikawa, Takahiro, Nakamura, Toru, Noji, Takehiro, Asano, Toshimichi, Tanaka, Kimitaka, Takayama, Kiyoshi, Hatanaka, Yutaka, Hirano, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Bile ducts Cancer CC chemokine receptors CCL19 protein CCR7 protein Cell differentiation Cell migration Cell receptors Chemokine receptors Chemokines Cholangiocarcinoma E-cadherin Health aspects Lymphatic system Medical prognosis Medical research Metastases Metastasis Molecular modelling Physiology Review boards Tumors Vimentin Western blotting Wound healing
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