Beneficial effect of monoclonal antibody to interleukin 2 receptor on activated T cells in rheumatoid arthritis

Campath 6, a rat IgG2b monoclonal antibody to the interleukin 2 receptor on activated T cells, was used to treat three patients with active rheumatoid arthritis unresponsive to conventional treatment. Two patients had an excellent response for about three months. There were no significant side effec...

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Veröffentlicht in:	Annals of the rheumatic diseases 1989-05, Vol.48 (5), p.428-429
Hauptverfasser:	Kyle, V, Coughlan, R J, Tighe, H, Waldmann, H, Hazleman, B L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies, Monoclonal - therapeutic use Arthritis, Rheumatoid - immunology Arthritis, Rheumatoid - physiopathology Arthritis, Rheumatoid - therapy Biological and medical sciences Diseases of the osteoarticular system Female Humans Inflammatory joint diseases Lymphocyte Activation Male Medical sciences Middle Aged Receptors, Interleukin-2 - immunology T-Lymphocytes - drug effects
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